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Genetic heterogeneity of the Spy1336/R28-Spy1337 virulence axis in Streptococcus pyogenes and effect on gene transcript levels and pathogenesis.
Eraso JM, Kachroo P, Olsen RJ, Beres SB, Zhu L, Badu T, Shannon S, Cantu CC, Saavedra MO, Kubiak SL, Porter AR, DeLeo FR, Musser JM. Eraso JM, et al. Among authors: cantu cc. PLoS One. 2020 Mar 26;15(3):e0229064. doi: 10.1371/journal.pone.0229064. eCollection 2020. PLoS One. 2020. PMID: 32214338 Free PMC article.
A naturally occurring single amino acid replacement in multiple gene regulator of group A Streptococcus significantly increases virulence.
Sanson M, O'Neill BE, Kachroo P, Anderson JR, Flores AR, Valson C, Cantu CC, Makthal N, Karmonik C, Fittipaldi N, Kumaraswami M, Musser JM, Olsen RJ. Sanson M, et al. Among authors: cantu cc. Am J Pathol. 2015 Feb;185(2):462-71. doi: 10.1016/j.ajpath.2014.10.018. Epub 2014 Dec 2. Am J Pathol. 2015. PMID: 25476528 Free PMC article.
Gene fitness landscape of group A streptococcus during necrotizing myositis.
Zhu L, Olsen RJ, Beres SB, Eraso JM, Saavedra MO, Kubiak SL, Cantu CC, Jenkins L, Charbonneau ARL, Waller AS, Musser JM. Zhu L, et al. Among authors: cantu cc. J Clin Invest. 2019 Feb 1;129(2):887-901. doi: 10.1172/JCI124994. Epub 2019 Jan 22. J Clin Invest. 2019. PMID: 30667377 Free PMC article.
Integrated analysis of population genomics, transcriptomics and virulence provides novel insights into Streptococcus pyogenes pathogenesis.
Kachroo P, Eraso JM, Beres SB, Olsen RJ, Zhu L, Nasser W, Bernard PE, Cantu CC, Saavedra MO, Arredondo MJ, Strope B, Do H, Kumaraswami M, Vuopio J, Gröndahl-Yli-Hannuksela K, Kristinsson KG, Gottfredsson M, Pesonen M, Pensar J, Davenport ER, Clark AG, Corander J, Caugant DA, Gaini S, Magnussen MD, Kubiak SL, Nguyen HAT, Long SW, Porter AR, DeLeo FR, Musser JM. Kachroo P, et al. Among authors: cantu cc. Nat Genet. 2019 Mar;51(3):548-559. doi: 10.1038/s41588-018-0343-1. Epub 2019 Feb 18. Nat Genet. 2019. PMID: 30778225 Free PMC article.
New Pathogenesis Mechanisms and Translational Leads Identified by Multidimensional Analysis of Necrotizing Myositis in Primates.
Kachroo P, Eraso JM, Olsen RJ, Zhu L, Kubiak SL, Pruitt L, Yerramilli P, Cantu CC, Ojeda Saavedra M, Pensar J, Corander J, Jenkins L, Kao L, Granillo A, Porter AR, DeLeo FR, Musser JM. Kachroo P, et al. Among authors: cantu cc. mBio. 2020 Feb 18;11(1):e03363-19. doi: 10.1128/mBio.03363-19. mBio. 2020. PMID: 32071274 Free PMC article.
Streptococcus pyogenes genes that promote pharyngitis in primates.
Zhu L, Olsen RJ, Beres SB, Saavedra MO, Kubiak SL, Cantu CC, Jenkins L, Waller AS, Sun Z, Palzkill T, Porter AR, DeLeo FR, Musser JM. Zhu L, et al. Among authors: cantu cc. JCI Insight. 2020 Jun 4;5(11):e137686. doi: 10.1172/jci.insight.137686. JCI Insight. 2020. PMID: 32493846 Free PMC article.
32 results