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A randomized proof-of-mechanism trial applying the 'fast-fail' approach to evaluating κ-opioid antagonism as a treatment for anhedonia.
Krystal AD, Pizzagalli DA, Smoski M, Mathew SJ, Nurnberger J Jr, Lisanby SH, Iosifescu D, Murrough JW, Yang H, Weiner RD, Calabrese JR, Sanacora G, Hermes G, Keefe RSE, Song A, Goodman W, Szabo ST, Whitton AE, Gao K, Potter WZ. Krystal AD, et al. Among authors: pizzagalli da. Nat Med. 2020 May;26(5):760-768. doi: 10.1038/s41591-020-0806-7. Epub 2020 Mar 30. Nat Med. 2020. PMID: 32231295 Free PMC article. Clinical Trial.
Illness progression, recent stress, and morphometry of hippocampal subfields and medial prefrontal cortex in major depression.
Treadway MT, Waskom ML, Dillon DG, Holmes AJ, Park MTM, Chakravarty MM, Dutra SJ, Polli FE, Iosifescu DV, Fava M, Gabrieli JDE, Pizzagalli DA. Treadway MT, et al. Among authors: pizzagalli da. Biol Psychiatry. 2015 Feb 1;77(3):285-294. doi: 10.1016/j.biopsych.2014.06.018. Epub 2014 Jul 3. Biol Psychiatry. 2015. PMID: 25109665 Free PMC article.
Anhedonia in melancholic and non-melancholic depressive disorders.
Fletcher K, Parker G, Paterson A, Fava M, Iosifescu D, Pizzagalli DA. Fletcher K, et al. Among authors: pizzagalli da. J Affect Disord. 2015 Sep 15;184:81-8. doi: 10.1016/j.jad.2015.05.028. Epub 2015 May 21. J Affect Disord. 2015. PMID: 26074016 Free PMC article.
Dynamic Resting-State Functional Connectivity in Major Depression.
Kaiser RH, Whitfield-Gabrieli S, Dillon DG, Goer F, Beltzer M, Minkel J, Smoski M, Dichter G, Pizzagalli DA. Kaiser RH, et al. Among authors: pizzagalli da. Neuropsychopharmacology. 2016 Jun;41(7):1822-30. doi: 10.1038/npp.2015.352. Epub 2015 Dec 3. Neuropsychopharmacology. 2016. PMID: 26632990 Free PMC article.
373 results