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CRISPRi-based radiation modifier screen identifies long non-coding RNA therapeutic targets in glioma.
Liu SJ, Malatesta M, Lien BV, Saha P, Thombare SS, Hong SJ, Pedraza L, Koontz M, Seo K, Horlbeck MA, He D, Birk HS, Jain M, Olsen HE, Akeson M, Weissman JS, Monje M, Gupta N, Raleigh DR, Ullian EM, Lim DA. Liu SJ, et al. Among authors: ullian em. Genome Biol. 2020 Mar 31;21(1):83. doi: 10.1186/s13059-020-01995-4. Genome Biol. 2020. PMID: 32234056 Free PMC article.
Multiplatform genomic profiling and magnetic resonance imaging identify mechanisms underlying intratumor heterogeneity in meningioma.
Magill ST, Vasudevan HN, Seo K, Villanueva-Meyer JE, Choudhury A, John Liu S, Pekmezci M, Findakly S, Hilz S, Lastella S, Demaree B, Braunstein SE, Bush NAO, Aghi MK, Theodosopoulos PV, Sneed PK, Abate AR, Berger MS, McDermott MW, Lim DA, Ullian EM, Costello JF, Raleigh DR. Magill ST, et al. Among authors: ullian em. Nat Commun. 2020 Sep 23;11(1):4803. doi: 10.1038/s41467-020-18582-7. Nat Commun. 2020. PMID: 32968068 Free PMC article.
CRISPRi screens in human iPSC-derived astrocytes elucidate regulators of distinct inflammatory reactive states.
Leng K, Rose IVL, Kim H, Xia W, Romero-Fernandez W, Rooney B, Koontz M, Li E, Ao Y, Wang S, Krawczyk M, Tcw J, Goate A, Zhang Y, Ullian EM, Sofroniew MV, Fancy SPJ, Schrag MS, Lippmann ES, Kampmann M. Leng K, et al. Among authors: ullian em. Nat Neurosci. 2022 Nov;25(11):1528-1542. doi: 10.1038/s41593-022-01180-9. Epub 2022 Oct 27. Nat Neurosci. 2022. PMID: 36303069 Free PMC article.
Zika virus cell tropism in the developing human brain and inhibition by azithromycin.
Retallack H, Di Lullo E, Arias C, Knopp KA, Laurie MT, Sandoval-Espinosa C, Mancia Leon WR, Krencik R, Ullian EM, Spatazza J, Pollen AA, Mandel-Brehm C, Nowakowski TJ, Kriegstein AR, DeRisi JL. Retallack H, et al. Among authors: ullian em. Proc Natl Acad Sci U S A. 2016 Dec 13;113(50):14408-14413. doi: 10.1073/pnas.1618029113. Epub 2016 Nov 29. Proc Natl Acad Sci U S A. 2016. PMID: 27911847 Free PMC article.
Dysregulation of astrocyte extracellular signaling in Costello syndrome.
Krencik R, Hokanson KC, Narayan AR, Dvornik J, Rooney GE, Rauen KA, Weiss LA, Rowitch DH, Ullian EM. Krencik R, et al. Among authors: ullian em. Sci Transl Med. 2015 May 6;7(286):286ra66. doi: 10.1126/scitranslmed.aaa5645. Sci Transl Med. 2015. PMID: 25947161 Free PMC article.
Astrocyte layers in the mammalian cerebral cortex revealed by a single-cell in situ transcriptomic map.
Bayraktar OA, Bartels T, Holmqvist S, Kleshchevnikov V, Martirosyan A, Polioudakis D, Ben Haim L, Young AMH, Batiuk MY, Prakash K, Brown A, Roberts K, Paredes MF, Kawaguchi R, Stockley JH, Sabeur K, Chang SM, Huang E, Hutchinson P, Ullian EM, Hemberg M, Coppola G, Holt MG, Geschwind DH, Rowitch DH. Bayraktar OA, et al. Among authors: ullian em. Nat Neurosci. 2020 Apr;23(4):500-509. doi: 10.1038/s41593-020-0602-1. Epub 2020 Mar 16. Nat Neurosci. 2020. PMID: 32203496 Free PMC article.
Neurotoxic microglia promote TDP-43 proteinopathy in progranulin deficiency.
Zhang J, Velmeshev D, Hashimoto K, Huang YH, Hofmann JW, Shi X, Chen J, Leidal AM, Dishart JG, Cahill MK, Kelley KW, Liddelow SA, Seeley WW, Miller BL, Walther TC, Farese RV Jr, Taylor JP, Ullian EM, Huang B, Debnath J, Wittmann T, Kriegstein AR, Huang EJ. Zhang J, et al. Among authors: ullian em. Nature. 2020 Dec;588(7838):459-465. doi: 10.1038/s41586-020-2709-7. Epub 2020 Aug 31. Nature. 2020. PMID: 32866962 Free PMC article.
56 results