Fang Y - Search Results

1

Nicotinamide mononucleotide adenylyltransferase uses its NAD⁺ substrate-binding site to chaperone phosphorylated Tau.

Ma X, Zhu Y, Lu J, Xie J, Li C, Shin WS, Qiang J, Liu J, Dou S, Xiao Y, Wang C, Jia C, Long H, Yang J, Fang Y, Jiang L, Zhang Y, Zhang S, Zhai RG, Liu C, Li D. Ma X, et al. Among authors: fang y. Elife. 2020 Apr 6;9:e51859. doi: 10.7554/eLife.51859. Elife. 2020. PMID: 32250733 Free PMC article.

2

PARylation regulates stress granule dynamics, phase separation, and neurotoxicity of disease-related RNA-binding proteins.

Duan Y, Du A, Gu J, Duan G, Wang C, Gui X, Ma Z, Qian B, Deng X, Zhang K, Sun L, Tian K, Zhang Y, Jiang H, Liu C, Fang Y. Duan Y, et al. Among authors: fang y. Cell Res. 2019 Mar;29(3):233-247. doi: 10.1038/s41422-019-0141-z. Epub 2019 Feb 6. Cell Res. 2019. PMID: 30728452 Free PMC article.

3

New insights of poly(ADP-ribosylation) in neurodegenerative diseases: A focus on protein phase separation and pathologic aggregation.

Liu C, Fang Y. Liu C, et al. Among authors: fang y. Biochem Pharmacol. 2019 Sep;167:58-63. doi: 10.1016/j.bcp.2019.04.028. Epub 2019 Apr 26. Biochem Pharmacol. 2019. PMID: 31034795 Review.

4

Multidimensional Proteomics Identifies Declines in Protein Homeostasis and Mitochondria as Early Signals for Normal Aging and Age-associated Disease in Drosophila.

Yang L, Cao Y, Zhao J, Fang Y, Liu N, Zhang Y. Yang L, et al. Among authors: fang y. Mol Cell Proteomics. 2019 Oct;18(10):2078-2088. doi: 10.1074/mcp.RA119.001621. Epub 2019 Aug 21. Mol Cell Proteomics. 2019. PMID: 31434710 Free PMC article.

5

Stress Induces Dynamic, Cytotoxicity-Antagonizing TDP-43 Nuclear Bodies via Paraspeckle LncRNA NEAT1-Mediated Liquid-Liquid Phase Separation.

Wang C, Duan Y, Duan G, Wang Q, Zhang K, Deng X, Qian B, Gu J, Ma Z, Zhang S, Guo L, Liu C, Fang Y. Wang C, et al. Among authors: fang y. Mol Cell. 2020 Aug 6;79(3):443-458.e7. doi: 10.1016/j.molcel.2020.06.019. Epub 2020 Jul 9. Mol Cell. 2020. PMID: 32649883 Free article.

6

Hsp40 proteins phase separate to chaperone the assembly and maintenance of membraneless organelles.

Gu J, Liu Z, Zhang S, Li Y, Xia W, Wang C, Xiang H, Liu Z, Tan L, Fang Y, Liu C, Li D. Gu J, et al. Among authors: fang y. Proc Natl Acad Sci U S A. 2020 Dec 8;117(49):31123-31133. doi: 10.1073/pnas.2002437117. Epub 2020 Nov 23. Proc Natl Acad Sci U S A. 2020. PMID: 33229560 Free PMC article.

7

The nuclear localization sequence mediates hnRNPA1 amyloid fibril formation revealed by cryoEM structure.

Sun Y, Zhao K, Xia W, Feng G, Gu J, Ma Y, Gui X, Zhang X, Fang Y, Sun B, Wang R, Liu C, Li D. Sun Y, et al. Among authors: fang y. Nat Commun. 2020 Dec 11;11(1):6349. doi: 10.1038/s41467-020-20227-8. Nat Commun. 2020. PMID: 33311513 Free PMC article.

8

Hsp70 chaperones TDP-43 in dynamic, liquid-like phase and prevents it from amyloid aggregation.

Gu J, Wang C, Hu R, Li Y, Zhang S, Sun Y, Wang Q, Li D, Fang Y, Liu C. Gu J, et al. Among authors: fang y. Cell Res. 2021 Sep;31(9):1024-1027. doi: 10.1038/s41422-021-00526-5. Epub 2021 Jul 8. Cell Res. 2021. PMID: 34239072 Free PMC article. No abstract available.

9

Selective Mitochondrial Protein Labeling Enabled by Biocompatible Photocatalytic Reactions inside Live Cells.

Wang H, Zhang Y, Zeng K, Qiang J, Cao Y, Li Y, Fang Y, Zhang Y, Chen Y. Wang H, et al. Among authors: fang y. JACS Au. 2021 Jun 14;1(7):1066-1075. doi: 10.1021/jacsau.1c00172. eCollection 2021 Jul 26. JACS Au. 2021. PMID: 34467350 Free PMC article.

10

The mouse nicotinamide mononucleotide adenylyltransferase chaperones diverse pathological amyloid client proteins.

Huang C, Lu J, Ma X, Qiang J, Wang C, Liu C, Fang Y, Zhang Y, Jiang L, Li D, Zhang S. Huang C, et al. Among authors: fang y. J Biol Chem. 2022 May;298(5):101912. doi: 10.1016/j.jbc.2022.101912. Epub 2022 Apr 7. J Biol Chem. 2022. PMID: 35398355 Free PMC article.

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