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Page 1
Placing CF2 in the Center: Major Physicochemical Changes Upon a Minor Structural Alteration in Gem-Difunctional Compounds.
Saphier S, Katalan S, Yacov G, Berliner A, Redy-Keisar O, Fridkin G, Ghindes-Azaria L, Columbus I, Pevzner A, Drug E, Prihed H, Gershonov E, Eichen Y, Elias S, Parvari G, Zafrani Y. Saphier S, et al. Among authors: zafrani y. Chemistry. 2023 Feb 1;29(7):e202202939. doi: 10.1002/chem.202202939. Epub 2022 Dec 12. Chemistry. 2023. PMID: 36374157
Species-specific lipophilicities of fluorinated diketones in complex equilibria systems and their potential as multifaceted reversible covalent warheads.
Columbus I, Ghindes-Azaria L, Herzog IM, Blum E, Parvari G, Eichen Y, Cohen Y, Gershonov E, Drug E, Saphier S, Elias S, Smolkin B, Zafrani Y. Columbus I, et al. Among authors: zafrani y. Commun Chem. 2023 Sep 15;6(1):197. doi: 10.1038/s42004-023-01004-2. Commun Chem. 2023. PMID: 37715018 Free PMC article.
Addressing the Opioids Lipophilicity Challenge via a Straightforward and Simultaneous 1H NMR-Based logP/D Determination, Both Separately and in Mixtures.
Yeffet D, Columbus I, Parvari G, Eichen Y, Saphier S, Ghindes-Azaria L, Redy-Keisar O, Amir D, Drug E, Gershonov E, Binyamin I, Cohen Y, Karton-Lifshin N, Zafrani Y. Yeffet D, et al. Among authors: zafrani y. J Med Chem. 2024 Jul 25;67(14):12399-12409. doi: 10.1021/acs.jmedchem.4c01153. Epub 2024 Jul 16. J Med Chem. 2024. PMID: 39013123
46 results