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Potent lipoprotein(a) lowering following apolipoprotein(a) antisense treatment reduces the pro-inflammatory activation of circulating monocytes in patients with elevated lipoprotein(a).
Stiekema LCA, Prange KHM, Hoogeveen RM, Verweij SL, Kroon J, Schnitzler JG, Dzobo KE, Cupido AJ, Tsimikas S, Stroes ESG, de Winther MPJ, Bahjat M. Stiekema LCA, et al. Among authors: hoogeveen rm. Eur Heart J. 2020 Jun 21;41(24):2262-2271. doi: 10.1093/eurheartj/ehaa171. Eur Heart J. 2020. PMID: 32268367 Free PMC article.
Cardiovascular disease risk associated with elevated lipoprotein(a) attenuates at low low-density lipoprotein cholesterol levels in a primary prevention setting.
Verbeek R, Hoogeveen RM, Langsted A, Stiekema LCA, Verweij SL, Hovingh GK, Wareham NJ, Khaw KT, Boekholdt SM, Nordestgaard BG, Stroes ESG. Verbeek R, et al. Among authors: hoogeveen rm. Eur Heart J. 2018 Jul 14;39(27):2589-2596. doi: 10.1093/eurheartj/ehy334. Eur Heart J. 2018. PMID: 29931232 Free PMC article.
Atherogenic Lipoprotein(a) Increases Vascular Glycolysis, Thereby Facilitating Inflammation and Leukocyte Extravasation.
Schnitzler JG, Hoogeveen RM, Ali L, Prange KHM, Waissi F, van Weeghel M, Bachmann JC, Versloot M, Borrelli MJ, Yeang C, De Kleijn DPV, Houtkooper RH, Koschinsky ML, de Winther MPJ, Groen AK, Witztum JL, Tsimikas S, Stroes ESG, Kroon J. Schnitzler JG, et al. Among authors: hoogeveen rm. Circ Res. 2020 May 8;126(10):1346-1359. doi: 10.1161/CIRCRESAHA.119.316206. Epub 2020 Mar 12. Circ Res. 2020. PMID: 32160811 Free PMC article.
Elevated Lp(a) (Lipoprotein[a]) Levels Increase Risk of 30-Day Major Adverse Cardiovascular Events in Patients Following Carotid Endarterectomy.
Waissi F, Dekker M, Timmerman N, Hoogeveen RM, van Bennekom J, Dzobo KE, Schnitzler JG, Pasterkamp G, Grobbee DE, de Borst GJ, Stroes ESG, de Kleijn DPV, Kroon J. Waissi F, et al. Among authors: hoogeveen rm. Stroke. 2020 Oct;51(10):2972-2982. doi: 10.1161/STROKEAHA.120.030616. Epub 2020 Sep 3. Stroke. 2020. PMID: 32878565 Free article.
Targeted proteomics improves cardiovascular risk prediction in secondary prevention.
Nurmohamed NS, Belo Pereira JP, Hoogeveen RM, Kroon J, Kraaijenhof JM, Waissi F, Timmerman N, Bom MJ, Hoefer IE, Knaapen P, Catapano AL, Koenig W, de Kleijn D, Visseren FLJ, Levin E, Stroes ESG. Nurmohamed NS, et al. Among authors: hoogeveen rm. Eur Heart J. 2022 Apr 19;43(16):1569-1577. doi: 10.1093/eurheartj/ehac055. Eur Heart J. 2022. PMID: 35139537 Free PMC article.
36 results