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Pharmacokinetics and pharmacodynamics of oral mecamylamine - development of a nicotinic acetylcholine receptor antagonist cognitive challenge test using modelling and simulation.
Alvarez-Jimenez R, Baakman AC, Stevens J, Goulooze SC, Hart EP, Rissmann R, van Gerven JM, Groeneveld GJ. Alvarez-Jimenez R, et al. Among authors: hart ep. J Psychopharmacol. 2017 Feb;31(2):192-203. doi: 10.1177/0269881116681417. Epub 2016 Dec 9. J Psychopharmacol. 2017. PMID: 27927703
Predictors of simulated driving performance in Huntington's disease.
Jacobs M, Hart EP, Mejia Miranda Y, Groeneveld GJ, van Gerven JMA, Roos RAC. Jacobs M, et al. Among authors: hart ep. Parkinsonism Relat Disord. 2019 Mar;60:64-69. doi: 10.1016/j.parkreldis.2018.10.002. Epub 2018 Oct 1. Parkinsonism Relat Disord. 2019. PMID: 30292732
Safety, pharmacokinetics and pharmacodynamics of SBT-020 in patients with early stage Huntington's disease, a 2-part study.
van Diemen MPJ, Hart EP, Abbruscato A, Mead L, van Beelen I, Bergheanu SC, Hameeteman PW, Coppen E, Winder JY, Moerland M, Kan H, van der Grond J, Webb A, Roos RAC, Groeneveld GJ. van Diemen MPJ, et al. Among authors: hart ep. Br J Clin Pharmacol. 2021 May;87(5):2290-2302. doi: 10.1111/bcp.14656. Epub 2020 Dec 29. Br J Clin Pharmacol. 2021. PMID: 33197078 Free PMC article. Clinical Trial.
63 results