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Page 1
Roadmap for the Emerging Field of Cancer Neuroscience.
Monje M, Borniger JC, D'Silva NJ, Deneen B, Dirks PB, Fattahi F, Frenette PS, Garzia L, Gutmann DH, Hanahan D, Hervey-Jumper SL, Hondermarck H, Hurov JB, Kepecs A, Knox SM, Lloyd AC, Magnon C, Saloman JL, Segal RA, Sloan EK, Sun X, Taylor MD, Tracey KJ, Trotman LC, Tuveson DA, Wang TC, White RA, Winkler F. Monje M, et al. Among authors: trotman lc. Cell. 2020 Apr 16;181(2):219-222. doi: 10.1016/j.cell.2020.03.034. Cell. 2020. PMID: 32302564 Free PMC article.
Identification of PHLPP1 as a tumor suppressor reveals the role of feedback activation in PTEN-mutant prostate cancer progression.
Chen M, Pratt CP, Zeeman ME, Schultz N, Taylor BS, O'Neill A, Castillo-Martin M, Nowak DG, Naguib A, Grace DM, Murn J, Navin N, Atwal GS, Sander C, Gerald WL, Cordon-Cardo C, Newton AC, Carver BS, Trotman LC. Chen M, et al. Among authors: trotman lc. Cancer Cell. 2011 Aug 16;20(2):173-86. doi: 10.1016/j.ccr.2011.07.013. Cancer Cell. 2011. PMID: 21840483 Free PMC article.
p53 mutations change phosphatidylinositol acyl chain composition.
Naguib A, Bencze G, Engle DD, Chio II, Herzka T, Watrud K, Bencze S, Tuveson DA, Pappin DJ, Trotman LC. Naguib A, et al. Among authors: trotman lc. Cell Rep. 2015 Jan 6;10(1):8-19. doi: 10.1016/j.celrep.2014.12.010. Epub 2014 Dec 24. Cell Rep. 2015. PMID: 25543136 Free PMC article.
The PHLPP2 phosphatase is a druggable driver of prostate cancer progression.
Nowak DG, Katsenelson KC, Watrud KE, Chen M, Mathew G, D'Andrea VD, Lee MF, Swamynathan MM, Casanova-Salas I, Jibilian MC, Buckholtz CL, Ambrico AJ, Pan CH, Wilkinson JE, Newton AC, Trotman LC. Nowak DG, et al. Among authors: trotman lc. J Cell Biol. 2019 Jun 3;218(6):1943-1957. doi: 10.1083/jcb.201902048. Epub 2019 May 15. J Cell Biol. 2019. PMID: 31092557 Free PMC article.
Bioactivation of Napabucasin Triggers Reactive Oxygen Species-Mediated Cancer Cell Death.
Froeling FEM, Swamynathan MM, Deschênes A, Chio IIC, Brosnan E, Yao MA, Alagesan P, Lucito M, Li J, Chang AY, Trotman LC, Belleau P, Park Y, Rogoff HA, Watson JD, Tuveson DA. Froeling FEM, et al. Among authors: trotman lc. Clin Cancer Res. 2019 Dec 1;25(23):7162-7174. doi: 10.1158/1078-0432.CCR-19-0302. Epub 2019 Sep 16. Clin Cancer Res. 2019. PMID: 31527169 Free PMC article.
SOAT1 promotes mevalonate pathway dependency in pancreatic cancer.
Oni TE, Biffi G, Baker LA, Hao Y, Tonelli C, Somerville TDD, Deschênes A, Belleau P, Hwang CI, Sánchez-Rivera FJ, Cox H, Brosnan E, Doshi A, Lumia RP, Khaledi K, Park Y, Trotman LC, Lowe SW, Krasnitz A, Vakoc CR, Tuveson DA. Oni TE, et al. Among authors: trotman lc. J Exp Med. 2020 Sep 7;217(9):e20192389. doi: 10.1084/jem.20192389. J Exp Med. 2020. PMID: 32633781 Free PMC article.
Next Directions in the Neuroscience of Cancers Arising outside the CNS.
Amit M, Anastasaki C, Dantzer R, Demir IE, Deneen B, Dixon KO, Egeblad M, Gibson EM, Hervey-Jumper SL, Hondermarck H, Magnon C, Monje M, Na'ara S, Pan Y, Repasky EA, Scheff NN, Sloan EK, Talbot S, Tracey KJ, Trotman LC, Valiente M, Van Aelst L, Venkataramani V, Venkatesh HS, Vermeer PD, Winkler F, Wong RJ, Gutmann DH, Borniger JC. Amit M, et al. Among authors: trotman lc. Cancer Discov. 2024 Apr 4;14(4):669-673. doi: 10.1158/2159-8290.CD-23-1495. Cancer Discov. 2024. PMID: 38571430
PTEN and p53: who will get the upper hand?
Trotman LC, Pandolfi PP. Trotman LC, et al. Cancer Cell. 2003 Feb;3(2):97-9. doi: 10.1016/s1535-6108(03)00022-9. Cancer Cell. 2003. PMID: 12620402 Free article. No abstract available.
NEDD4-1 is a proto-oncogenic ubiquitin ligase for PTEN.
Wang X, Trotman LC, Koppie T, Alimonti A, Chen Z, Gao Z, Wang J, Erdjument-Bromage H, Tempst P, Cordon-Cardo C, Pandolfi PP, Jiang X. Wang X, et al. Among authors: trotman lc. Cell. 2007 Jan 12;128(1):129-39. doi: 10.1016/j.cell.2006.11.039. Cell. 2007. PMID: 17218260 Free PMC article.
56 results