Wang Z - Search Results

1

Ubiquitination-activating enzymes UBE1 and UBA6 regulate ubiquitination and expression of cardiac sodium channel Nav1.5.

Hu Y, Bai X, Zhang C, Chakrabarti S, Tang B, Xiong H, Wang Z, Yu G, Xu C, Chen Q, Wang QK. Hu Y, et al. Among authors: wang z, wang qk. Biochem J. 2020 May 15;477(9):1683-1700. doi: 10.1042/BCJ20200138. Biochem J. 2020. PMID: 32315024

2

Post-transcriptional regulation of cardiac sodium channel gene SCN5A expression and function by miR-192-5p.

Zhao Y, Huang Y, Li W, Wang Z, Zhan S, Zhou M, Yao Y, Zeng Z, Hou Y, Chen Q, Tu X, Wang QK, Huang Z. Zhao Y, et al. Among authors: wang z, wang qk. Biochim Biophys Acta. 2015 Oct;1852(10 Pt A):2024-34. doi: 10.1016/j.bbadis.2015.07.016. Epub 2015 Jul 21. Biochim Biophys Acta. 2015. PMID: 26209011 Free PMC article.

3

αB-Crystallin Interacts with Nav1.5 and Regulates Ubiquitination and Internalization of Cell Surface Nav1.5.

Huang Y, Wang Z, Liu Y, Xiong H, Zhao Y, Wu L, Yuan C, Wang L, Hou Y, Yu G, Huang Z, Xu C, Chen Q, Wang QK. Huang Y, et al. Among authors: wang l, wang z, wang qk. J Biol Chem. 2016 May 20;291(21):11030-41. doi: 10.1074/jbc.M115.695080. Epub 2016 Mar 9. J Biol Chem. 2016. PMID: 26961874 Free PMC article.

4

Small GTPases SAR1A and SAR1B regulate the trafficking of the cardiac sodium channel Na_v1.5.

Wang Z, Yu G, Liu Y, Liu S, Aridor M, Huang Y, Hu Y, Wang L, Li S, Xiong H, Tang B, Li X, Cheng C, Chakrabarti S, Wang F, Wu Q, Karnik SS, Xu C, Chen Q, Wang QK. Wang Z, et al. Among authors: wang f, wang l, wang qk. Biochim Biophys Acta Mol Basis Dis. 2018 Nov;1864(11):3672-3684. doi: 10.1016/j.bbadis.2018.09.003. Epub 2018 Sep 6. Biochim Biophys Acta Mol Basis Dis. 2018. PMID: 30251687 Free PMC article.

5

Mechanistic insights into the interaction of the MOG1 protein with the cardiac sodium channel Na_v1.5 clarify the molecular basis of Brugada syndrome.

Yu G, Liu Y, Qin J, Wang Z, Hu Y, Wang F, Li Y, Chakrabarti S, Chen Q, Wang QK. Yu G, et al. Among authors: wang f, wang z, wang qk. J Biol Chem. 2018 Nov 23;293(47):18207-18217. doi: 10.1074/jbc.RA118.003997. Epub 2018 Oct 3. J Biol Chem. 2018. PMID: 30282806 Free PMC article.

6

UBC9 regulates cardiac sodium channel Na_v1.5 ubiquitination, degradation and sodium current density.

Tang B, Hu Y, Wang Z, Cheng C, Wang P, Liang L, Xiong H, Luo C, Xu C, Chen Q, Wang QK. Tang B, et al. Among authors: wang z, wang p, wang qk. J Mol Cell Cardiol. 2019 Apr;129:79-91. doi: 10.1016/j.yjmcc.2019.02.007. Epub 2019 Feb 14. J Mol Cell Cardiol. 2019. PMID: 30772377 Free PMC article.

7

Identification of rare variants in cardiac sodium channel β4-subunit gene SCN4B associated with ventricular tachycardia.

Yang Q, Xiong H, Xu C, Huang Y, Tu X, Wu G, Fu F, Wang Z, Wang L, Zhao Y, Li S, Huang Y, Wang C, Wang D, Yao Y, Wang F, Wang Y, Xue Y, Wang P, Chen Q, Pu J, Wang QK. Yang Q, et al. Among authors: wang f, wang l, wang z, wang y, wang p, wang d, wang c, wang qk. Mol Genet Genomics. 2019 Aug;294(4):1059-1071. doi: 10.1007/s00438-019-01567-7. Epub 2019 Apr 17. Mol Genet Genomics. 2019. PMID: 31020414 Free PMC article.

8

Mog1 knockout causes cardiac hypertrophy and heart failure by downregulating tbx5-cryab-hspb2 signalling in zebrafish.

Gou D, Zhou J, Song Q, Wang Z, Bai X, Zhang Y, Zuo M, Wang F, Chen A, Yousaf M, Yang Z, Peng H, Li K, Xie W, Tang J, Yao Y, Han M, Ke T, Chen Q, Xu C, Wang Q. Gou D, et al. Among authors: wang f, wang z, wang q. Acta Physiol (Oxf). 2021 Mar;231(3):e13567. doi: 10.1111/apha.13567. Epub 2020 Oct 22. Acta Physiol (Oxf). 2021. PMID: 33032360

9

Mechanistic insights into the interaction of cardiac sodium channel Na_v1.5 with MOG1 and a new molecular mechanism for Brugada syndrome.

Xiong H, Bai X, Quan Z, Yu D, Zhang H, Zhang C, Liang L, Yao Y, Yang Q, Wang Z, Wang L, Huang Y, Li H, Ren X, Tu X, Ke T, Xu C, Wang QK. Xiong H, et al. Among authors: wang l, wang z, wang qk. Heart Rhythm. 2022 Mar;19(3):478-489. doi: 10.1016/j.hrthm.2021.11.026. Epub 2021 Nov 26. Heart Rhythm. 2022. PMID: 34843967

10

Gene therapy targeting protein trafficking regulator MOG1 in mouse models of Brugada syndrome, arrhythmias, and mild cardiomyopathy.

Yu G, Chakrabarti S, Tischenko M, Chen AL, Wang Z, Cho H, French BA, Naga Prasad SV, Chen Q, Wang QK. Yu G, et al. Among authors: wang z, wang qk. Sci Transl Med. 2022 Jun 8;14(648):eabf3136. doi: 10.1126/scitranslmed.abf3136. Epub 2022 Jun 8. Sci Transl Med. 2022. PMID: 35675436

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