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Structure-based design of antiviral drug candidates targeting the SARS-CoV-2 main protease.
Dai W, Zhang B, Jiang XM, Su H, Li J, Zhao Y, Xie X, Jin Z, Peng J, Liu F, Li C, Li Y, Bai F, Wang H, Cheng X, Cen X, Hu S, Yang X, Wang J, Liu X, Xiao G, Jiang H, Rao Z, Zhang LK, Xu Y, Yang H, Liu H. Dai W, et al. Among authors: liu x, liu h, liu f. Science. 2020 Jun 19;368(6497):1331-1335. doi: 10.1126/science.abb4489. Epub 2020 Apr 22. Science. 2020. PMID: 32321856 Free PMC article.
Crystal structure of Junin virus nucleoprotein.
Zhang Y, Li L, Liu X, Dong S, Wang W, Huo T, Guo Y, Rao Z, Yang C. Zhang Y, et al. Among authors: liu x. J Gen Virol. 2013 Oct;94(Pt 10):2175-2183. doi: 10.1099/vir.0.055053-0. Epub 2013 Jul 24. J Gen Virol. 2013. PMID: 23884367
Structural basis for replicase polyprotein cleavage and substrate specificity of main protease from SARS-CoV-2.
Zhao Y, Zhu Y, Liu X, Jin Z, Duan Y, Zhang Q, Wu C, Feng L, Du X, Zhao J, Shao M, Zhang B, Yang X, Wu L, Ji X, Guddat LW, Yang K, Rao Z, Yang H. Zhao Y, et al. Among authors: liu x. Proc Natl Acad Sci U S A. 2022 Apr 19;119(16):e2117142119. doi: 10.1073/pnas.2117142119. Epub 2022 Apr 5. Proc Natl Acad Sci U S A. 2022. PMID: 35380892 Free PMC article.
Molecular mechanisms of SARS-CoV-2 resistance to nirmatrelvir.
Duan Y, Zhou H, Liu X, Iketani S, Lin M, Zhang X, Bian Q, Wang H, Sun H, Hong SJ, Culbertson B, Mohri H, Luck MI, Zhu Y, Liu X, Lu Y, Yang X, Yang K, Sabo Y, Chavez A, Goff SP, Rao Z, Ho DD, Yang H. Duan Y, et al. Among authors: liu x. Nature. 2023 Oct;622(7982):376-382. doi: 10.1038/s41586-023-06609-0. Epub 2023 Sep 11. Nature. 2023. PMID: 37696289
137,304 results
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