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The L-α-Lysophosphatidylinositol/G Protein-Coupled Receptor 55 System Induces the Development of Nonalcoholic Steatosis and Steatohepatitis.
Fondevila MF, Fernandez U, Gonzalez-Rellan MJ, Da Silva Lima N, Buque X, Gonzalez-Rodriguez A, Alonso C, Iruarrizaga-Lejarreta M, Delgado TC, Varela-Rey M, Senra A, Garcia-Outeiral V, Novoa E, Iglesias C, Porteiro B, Beiroa D, Folgueira C, Tojo M, Torres JL, Hernández-Cosido L, Blanco Ó, Arab JP, Barrera F, Guallar D, Fidalgo M, López M, Dieguez C, Marcos M, Martinez-Chantar ML, Arrese M, Garcia-Monzon C, Mato JM, Aspichueta P, Nogueiras R. Fondevila MF, et al. Among authors: folgueira c. Hepatology. 2021 Feb;73(2):606-624. doi: 10.1002/hep.31290. Epub 2020 Nov 13. Hepatology. 2021. PMID: 32329085 Free PMC article.
p38α kinase governs muscle strength through PGC1α in mice.
Herrera-Melle L, Cicuéndez B, López JA, Dumesic PA, Wilensky SE, Rodríguez E, Leiva-Vega L, Caballero A, León M, Vázquez J, Spiegelman BM, Folgueira C, Mora A, Sabio G. Herrera-Melle L, et al. Among authors: folgueira c. Acta Physiol (Oxf). 2024 Nov;240(11):e14234. doi: 10.1111/apha.14234. Epub 2024 Oct 3. Acta Physiol (Oxf). 2024. PMID: 39361268
Hypothalamic κ-opioid receptor modulates the orexigenic effect of ghrelin.
Romero-Picó A, Vázquez MJ, González-Touceda D, Folgueira C, Skibicka KP, Alvarez-Crespo M, Van Gestel MA, Velásquez DA, Schwarzer C, Herzog H, López M, Adan RA, Dickson SL, Diéguez C, Nogueiras R. Romero-Picó A, et al. Among authors: folgueira c. Neuropsychopharmacology. 2013 Jun;38(7):1296-307. doi: 10.1038/npp.2013.28. Epub 2013 Jan 24. Neuropsychopharmacology. 2013. PMID: 23348063 Free PMC article.
Circulating Betatrophin Levels Are Increased in Anorexia and Decreased in Morbidly Obese Women.
Barja-Fernández S, Folgueira C, Seoane LM, Casanueva FF, Dieguez C, Castelao C, Agüera Z, Baños R, Botella C, de la Torre R, Fernández-García JC, Fernández-Real JM, Frühbeck G, Gómez-Ambrosi J, Jiménez-Murcia S, Tinahones FJ, Estivill X, Fernández-Aranda F, Nogueiras R. Barja-Fernández S, et al. Among authors: folgueira c. J Clin Endocrinol Metab. 2015 Sep;100(9):E1188-96. doi: 10.1210/JC.2015-1595. Epub 2015 Jul 14. J Clin Endocrinol Metab. 2015. PMID: 26171798
Hypothalamic kappa opioid receptor mediates both diet-induced and melanin concentrating hormone-induced liver damage through inflammation and endoplasmic reticulum stress.
Imbernon M, Sanchez-Rebordelo E, Romero-Picó A, Kalló I, Chee MJ, Porteiro B, Al-Massadi O, Contreras C, Fernø J, Senra A, Gallego R, Folgueira C, Seoane LM, van Gestel M, Adan RA, Liposits Z, Dieguez C, López M, Nogueiras R. Imbernon M, et al. Among authors: folgueira c. Hepatology. 2016 Oct;64(4):1086-104. doi: 10.1002/hep.28716. Epub 2016 Aug 9. Hepatology. 2016. PMID: 27387967 Free PMC article.
Pharmacological inhibition of cannabinoid receptor 1 stimulates gastric release of nesfatin-1 via the mTOR pathway.
Folgueira C, Barja-Fernandez S, Prado L, Al-Massadi O, Castelao C, Pena-Leon V, Gonzalez-Saenz P, Baltar J, Baamonde I, Leis R, Dieguez C, Pagotto U, Casanueva FF, Tovar SA, Nogueiras R, Seoane LM. Folgueira C, et al. World J Gastroenterol. 2017 Sep 21;23(35):6403-6411. doi: 10.3748/wjg.v23.i35.6403. World J Gastroenterol. 2017. PMID: 29085189 Free PMC article.
Melanin-Concentrating Hormone acts through hypothalamic kappa opioid system and p70S6K to stimulate acute food intake.
Romero-Picó A, Sanchez-Rebordelo E, Imbernon M, González-Touceda D, Folgueira C, Senra A, Fernø J, Blouet C, Cabrera R, van Gestel M, Adan RA, López M, Maldonado R, Nogueiras R, Diéguez C. Romero-Picó A, et al. Among authors: folgueira c. Neuropharmacology. 2018 Mar 1;130:62-70. doi: 10.1016/j.neuropharm.2017.11.040. Epub 2017 Dec 2. Neuropharmacology. 2018. PMID: 29191753
62 results