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Regulatory T Cells License Macrophage Pro-Resolving Functions During Atherosclerosis Regression.
Sharma M, Schlegel MP, Afonso MS, Brown EJ, Rahman K, Weinstock A, Sansbury BE, Corr EM, van Solingen C, Koelwyn GJ, Shanley LC, Beckett L, Peled D, Lafaille JJ, Spite M, Loke P, Fisher EA, Moore KJ. Sharma M, et al. Circ Res. 2020 Jul 17;127(3):335-353. doi: 10.1161/CIRCRESAHA.119.316461. Epub 2020 Apr 27. Circ Res. 2020. PMID: 32336197 Free PMC article.
Single-Cell RNA Sequencing of Visceral Adipose Tissue Leukocytes Reveals that Caloric Restriction Following Obesity Promotes the Accumulation of a Distinct Macrophage Population with Features of Phagocytic Cells.
Weinstock A, Brown EJ, Garabedian ML, Pena S, Sharma M, Lafaille J, Moore KJ, Fisher EA. Weinstock A, et al. Among authors: sharma m. Immunometabolism. 2019;1:e190008. doi: 10.20900/immunometab20190008. Epub 2019 Jul 19. Immunometabolism. 2019. PMID: 31396408 Free PMC article.
The long noncoding RNA CHROME regulates cholesterol homeostasis in primate.
Hennessy EJ, van Solingen C, Scacalossi KR, Ouimet M, Afonso MS, Prins J, Koelwyn GJ, Sharma M, Ramkhelawon B, Carpenter S, Busch A, Chernogubova E, Matic LP, Hedin U, Maegdefessel L, Caffrey BE, Hussein MA, Ricci EP, Temel RE, Garabedian MJ, Berger JS, Vickers KC, Kanke M, Sethupathy P, Teupser D, Holdt LM, Moore KJ. Hennessy EJ, et al. Among authors: sharma m. Nat Metab. 2019 Jan;1(1):98-110. doi: 10.1038/s42255-018-0004-9. Epub 2018 Dec 3. Nat Metab. 2019. PMID: 31410392 Free PMC article.
Netrin-1 Alters Adipose Tissue Macrophage Fate and Function in Obesity.
Sharma M, Schlegel M, Brown EJ, Sansbury BE, Weinstock A, Afonso MS, Corr EM, van Solingen C, Shanley LC, Peled D, Ramasamy R, Schmidt AM, Spite M, Fisher EA, Moore KJ. Sharma M, et al. Immunometabolism. 2019;1(2):e190010. doi: 10.20900/immunometab20190010. Epub 2019 Aug 7. Immunometabolism. 2019. PMID: 31428465 Free PMC article.
Myocardial infarction accelerates breast cancer via innate immune reprogramming.
Koelwyn GJ, Newman AAC, Afonso MS, van Solingen C, Corr EM, Brown EJ, Albers KB, Yamaguchi N, Narke D, Schlegel M, Sharma M, Shanley LC, Barrett TJ, Rahman K, Mezzano V, Fisher EA, Park DS, Newman JD, Quail DF, Nelson ER, Caan BJ, Jones LW, Moore KJ. Koelwyn GJ, et al. Among authors: sharma m. Nat Med. 2020 Sep;26(9):1452-1458. doi: 10.1038/s41591-020-0964-7. Epub 2020 Jul 13. Nat Med. 2020. PMID: 32661390 Free PMC article.
miR-33 Silencing Reprograms the Immune Cell Landscape in Atherosclerotic Plaques.
Afonso MS, Sharma M, Schlegel M, van Solingen C, Koelwyn GJ, Shanley LC, Beckett L, Peled D, Rahman K, Giannarelli C, Li H, Brown EJ, Khodadadi-Jamayran A, Fisher EA, Moore KJ. Afonso MS, et al. Among authors: sharma m. Circ Res. 2021 Apr 16;128(8):1122-1138. doi: 10.1161/CIRCRESAHA.120.317914. Epub 2021 Feb 17. Circ Res. 2021. PMID: 33593073 Free PMC article.
MicroRNA-33 Inhibits Adaptive Thermogenesis and Adipose Tissue Beiging.
Afonso MS, Verma N, van Solingen C, Cyr Y, Sharma M, Perie L, Corr EM, Schlegel M, Shanley LC, Peled D, Yoo JY, Schmidt AM, Mueller E, Moore KJ. Afonso MS, et al. Among authors: sharma m. Arterioscler Thromb Vasc Biol. 2021 Apr;41(4):1360-1373. doi: 10.1161/ATVBAHA.120.315798. Epub 2021 Mar 4. Arterioscler Thromb Vasc Biol. 2021. PMID: 33657886 Free PMC article.
Silencing Myeloid Netrin-1 Induces Inflammation Resolution and Plaque Regression.
Schlegel M, Sharma M, Brown EJ, Newman AAC, Cyr Y, Afonso MS, Corr EM, Koelwyn GJ, van Solingen C, Guzman J, Farhat R, Nikain CA, Shanley LC, Peled D, Schmidt AM, Fisher EA, Moore KJ. Schlegel M, et al. Among authors: sharma m. Circ Res. 2021 Aug 20;129(5):530-546. doi: 10.1161/CIRCRESAHA.121.319313. Epub 2021 Jul 22. Circ Res. 2021. PMID: 34289717 Free PMC article.
Targeting Unc5b in macrophages drives atherosclerosis regression and pro-resolving immune cell function.
Schlegel M, Cyr Y, Newman AAC, Schreyer K, Barcia Durán JG, Sharma M, Bozal FK, Gourvest M, La Forest M, Afonso MS, van Solingen C, Fisher EA, Moore KJ. Schlegel M, et al. Among authors: sharma m. Proc Natl Acad Sci U S A. 2024 Oct 29;121(44):e2412690121. doi: 10.1073/pnas.2412690121. Epub 2024 Oct 22. Proc Natl Acad Sci U S A. 2024. PMID: 39436659 Free PMC article.
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