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Selective Alanine Transporter Utilization Creates a Targetable Metabolic Niche in Pancreatic Cancer.
Parker SJ, Amendola CR, Hollinshead KER, Yu Q, Yamamoto K, Encarnación-Rosado J, Rose RE, LaRue MM, Sohn ASW, Biancur DE, Paulo JA, Gygi SP, Jones DR, Wang H, Philips MR, Bar-Sagi D, Mancias JD, Kimmelman AC. Parker SJ, et al. Cancer Discov. 2020 Jul;10(7):1018-1037. doi: 10.1158/2159-8290.CD-19-0959. Epub 2020 Apr 27. Cancer Discov. 2020. PMID: 32341021 Free PMC article.
Ras/MAPK signaling from endomembranes.
Fehrenbacher N, Bar-Sagi D, Philips M. Fehrenbacher N, et al. Mol Oncol. 2009 Aug;3(4):297-307. doi: 10.1016/j.molonc.2009.06.004. Epub 2009 Jun 26. Mol Oncol. 2009. PMID: 19615955 Free PMC article. Review.
Regulation of RAS oncogenicity by acetylation.
Yang MH, Nickerson S, Kim ET, Liot C, Laurent G, Spang R, Philips MR, Shan Y, Shaw DE, Bar-Sagi D, Haigis MC, Haigis KM. Yang MH, et al. Proc Natl Acad Sci U S A. 2012 Jul 3;109(27):10843-8. doi: 10.1073/pnas.1201487109. Epub 2012 Jun 18. Proc Natl Acad Sci U S A. 2012. PMID: 22711838 Free PMC article.
Macropinocytosis of protein is an amino acid supply route in Ras-transformed cells.
Commisso C, Davidson SM, Soydaner-Azeloglu RG, Parker SJ, Kamphorst JJ, Hackett S, Grabocka E, Nofal M, Drebin JA, Thompson CB, Rabinowitz JD, Metallo CM, Vander Heiden MG, Bar-Sagi D. Commisso C, et al. Nature. 2013 May 30;497(7451):633-7. doi: 10.1038/nature12138. Epub 2013 May 12. Nature. 2013. PMID: 23665962 Free PMC article.
IL35-Producing B Cells Promote the Development of Pancreatic Neoplasia.
Pylayeva-Gupta Y, Das S, Handler JS, Hajdu CH, Coffre M, Koralov SB, Bar-Sagi D. Pylayeva-Gupta Y, et al. Cancer Discov. 2016 Mar;6(3):247-55. doi: 10.1158/2159-8290.CD-15-0843. Epub 2015 Dec 29. Cancer Discov. 2016. PMID: 26715643 Free PMC article.
184 results