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Page 1
CDK12 inhibition reduces abnormalities in cells from patients with myotonic dystrophy and in a mouse model.
Ketley A, Wojciechowska M, Ghidelli-Disse S, Bamborough P, Ghosh TK, Morato ML, Sedehizadeh S, Malik NA, Tang Z, Powalowska P, Tanner M, Billeter-Clark R, Trueman RC, Geiszler PC, Agostini A, Othman O, Bösche M, Bantscheff M, Rüdiger M, Mossakowska DE, Drewry DH, Zuercher WJ, Thornton CA, Drewes G, Uings I, Hayes CJ, Brook JD. Ketley A, et al. Among authors: thornton ca. Sci Transl Med. 2020 Apr 29;12(541):eaaz2415. doi: 10.1126/scitranslmed.aaz2415. Sci Transl Med. 2020. PMID: 32350131
The myotonic dystrophies.
Thornton C. Thornton C. Semin Neurol. 1999;19(1):25-33. doi: 10.1055/s-2008-1040823. Semin Neurol. 1999. PMID: 10711986 Review.
Myotonic syndromes.
Mankodi A, Thornton CA. Mankodi A, et al. Among authors: thornton ca. Curr Opin Neurol. 2002 Oct;15(5):545-52. doi: 10.1097/00019052-200210000-00005. Curr Opin Neurol. 2002. PMID: 12351998 Review.
Nuclear RNA foci in the heart in myotonic dystrophy.
Mankodi A, Lin X, Blaxall BC, Swanson MS, Thornton CA. Mankodi A, et al. Among authors: thornton ca. Circ Res. 2005 Nov 25;97(11):1152-5. doi: 10.1161/01.RES.0000193598.89753.e3. Epub 2005 Oct 27. Circ Res. 2005. PMID: 16254211
Myotonic dystrophy: RNA-mediated muscle disease.
Wheeler TM, Thornton CA. Wheeler TM, et al. Among authors: thornton ca. Curr Opin Neurol. 2007 Oct;20(5):572-6. doi: 10.1097/WCO.0b013e3282ef6064. Curr Opin Neurol. 2007. PMID: 17885447 Review.
245 results