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Mutation position is an important determinant for predicting cancer neoantigens.
Capietto AH, Jhunjhunwala S, Pollock SB, Lupardus P, Wong J, Hänsch L, Cevallos J, Chestnut Y, Fernandez A, Lounsbury N, Nozawa T, Singh M, Fan Z, de la Cruz CC, Phung QT, Taraborrelli L, Haley B, Lill JR, Mellman I, Bourgon R, Delamarre L. Capietto AH, et al. Among authors: delamarre l. J Exp Med. 2020 Apr 6;217(4):e20190179. doi: 10.1084/jem.20190179. J Exp Med. 2020. PMID: 31940002 Free PMC article.
IL-1 and IL-1ra are key regulators of the inflammatory response to RNA vaccines.
Tahtinen S, Tong AJ, Himmels P, Oh J, Paler-Martinez A, Kim L, Wichner S, Oei Y, McCarron MJ, Freund EC, Amir ZA, de la Cruz CC, Haley B, Blanchette C, Schartner JM, Ye W, Yadav M, Sahin U, Delamarre L, Mellman I. Tahtinen S, et al. Among authors: delamarre l. Nat Immunol. 2022 Apr;23(4):532-542. doi: 10.1038/s41590-022-01160-y. Epub 2022 Mar 24. Nat Immunol. 2022. PMID: 35332327
Harnessing dendritic cells for immunotherapy.
Delamarre L, Mellman I. Delamarre L, et al. Semin Immunol. 2011 Feb;23(1):2-11. doi: 10.1016/j.smim.2011.02.001. Epub 2011 Mar 5. Semin Immunol. 2011. PMID: 21377379 Review.
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