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Page 1
Neutralizing human antibodies prevent Zika virus replication and fetal disease in mice.
Sapparapu G, Fernandez E, Kose N, Bin Cao, Fox JM, Bombardi RG, Zhao H, Nelson CA, Bryan AL, Barnes T, Davidson E, Mysorekar IU, Fremont DH, Doranz BJ, Diamond MS, Crowe JE. Sapparapu G, et al. Nature. 2016 Dec 15;540(7633):443-447. doi: 10.1038/nature20564. Epub 2016 Nov 7. Nature. 2016. PMID: 27819683 Free PMC article.
A lipid-encapsulated mRNA encoding a potently neutralizing human monoclonal antibody protects against chikungunya infection.
Kose N, Fox JM, Sapparapu G, Bombardi R, Tennekoon RN, de Silva AD, Elbashir SM, Theisen MA, Humphris-Narayanan E, Ciaramella G, Himansu S, Diamond MS, Crowe JE Jr. Kose N, et al. Among authors: bombardi r. Sci Immunol. 2019 May 17;4(35):eaaw6647. doi: 10.1126/sciimmunol.aaw6647. Sci Immunol. 2019. PMID: 31101672 Free PMC article.
Human mAbs Broadly Protect against Arthritogenic Alphaviruses by Recognizing Conserved Elements of the Mxra8 Receptor-Binding Site.
Powell LA, Miller A, Fox JM, Kose N, Klose T, Kim AS, Bombardi R, Tennekoon RN, Dharshan de Silva A, Carnahan RH, Diamond MS, Rossmann MG, Kuhn RJ, Crowe JE Jr. Powell LA, et al. Among authors: bombardi r. Cell Host Microbe. 2020 Nov 11;28(5):699-711.e7. doi: 10.1016/j.chom.2020.07.008. Epub 2020 Aug 11. Cell Host Microbe. 2020. PMID: 32783883 Free PMC article.
Human Antibodies Protect against Aerosolized Eastern Equine Encephalitis Virus Infection.
Williamson LE, Gilliland T Jr, Yadav PK, Binshtein E, Bombardi R, Kose N, Nargi RS, Sutton RE, Durie CL, Armstrong E, Carnahan RH, Walker LM, Kim AS, Fox JM, Diamond MS, Ohi MD, Klimstra WB, Crowe JE Jr. Williamson LE, et al. Among authors: bombardi r. Cell. 2020 Dec 23;183(7):1884-1900.e23. doi: 10.1016/j.cell.2020.11.011. Epub 2020 Dec 9. Cell. 2020. PMID: 33301709 Free PMC article.
Multifunctional Pan-ebolavirus Antibody Recognizes a Site of Broad Vulnerability on the Ebolavirus Glycoprotein.
Gilchuk P, Kuzmina N, Ilinykh PA, Huang K, Gunn BM, Bryan A, Davidson E, Doranz BJ, Turner HL, Fusco ML, Bramble MS, Hoff NA, Binshtein E, Kose N, Flyak AI, Flinko R, Orlandi C, Carnahan R, Parrish EH, Sevy AM, Bombardi RG, Singh PK, Mukadi P, Muyembe-Tamfum JJ, Ohi MD, Saphire EO, Lewis GK, Alter G, Ward AB, Rimoin AW, Bukreyev A, Crowe JE Jr. Gilchuk P, et al. Among authors: bombardi rg. Immunity. 2018 Aug 21;49(2):363-374.e10. doi: 10.1016/j.immuni.2018.06.018. Epub 2018 Jul 17. Immunity. 2018. PMID: 30029854 Free PMC article.
Influenza H7N9 Virus Neuraminidase-Specific Human Monoclonal Antibodies Inhibit Viral Egress and Protect from Lethal Influenza Infection in Mice.
Gilchuk IM, Bangaru S, Gilchuk P, Irving RP, Kose N, Bombardi RG, Thornburg NJ, Creech CB, Edwards KM, Li S, Turner HL, Yu W, Zhu X, Wilson IA, Ward AB, Crowe JE Jr. Gilchuk IM, et al. Cell Host Microbe. 2019 Dec 11;26(6):715-728.e8. doi: 10.1016/j.chom.2019.10.003. Epub 2019 Nov 19. Cell Host Microbe. 2019. PMID: 31757769 Free PMC article.
Integrated pipeline for the accelerated discovery of antiviral antibody therapeutics.
Gilchuk P, Bombardi RG, Erasmus JH, Tan Q, Nargi R, Soto C, Abbink P, Suscovich TJ, Durnell LA, Khandhar A, Archer J, Liang J, Fouch ME, Davidson E, Doranz BJ, Jones T, Larson E, Ertel S, Granger B, Fuerte-Stone J, Roy V, Broge T, Linnekin TC, Linde CH, Gorman MJ, Nkolola J, Alter G, Reed SG, Barouch DH, Diamond MS, Crowe JE Jr, Van Hoeven N, Thackray LB, Carnahan RH. Gilchuk P, et al. Among authors: bombardi rg. Nat Biomed Eng. 2020 Nov;4(11):1030-1043. doi: 10.1038/s41551-020-0594-x. Epub 2020 Aug 3. Nat Biomed Eng. 2020. PMID: 32747832 Free PMC article.
56 results