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Page 1
Cerebral Microbleeds and Amyloid Pathology Estimates From the Amyloid Biomarker Study.
Oomens JE, van Gils V, Vos SJB, Freeze WM, Maserejian NN, Curiale G, Gillis C, Boada M, van der Flier WM, Hort J, Johnson SC, Lleó A, Ramakers IH, Rodrigue KM, Sánchez-Juan P, Sarazin M, Scarmeas N, Zetterberg H, Alcolea D, Barkhof F, Blennow K, Bottlaender M, den Braber A, Cerman J, Drake-Perez M, Fortea J, Handels R, Ingala S, Jiménez-Bonilla JF, Karavasilis S, Lagarde J, Legdeur N, Lorenzini L, Marquié M, Moonen JEF, Olivieri P, Orellana A, Ossenkoppele R, Rivera-Rivera LA, Rodríguez-Rodriguez E, Ruiz Laza A, Teunissen CE, Tijms BM, Velonakis G, Verhey FRJ, Visser PJ, Jansen WJ; European Prevention of Alzheimer’s Dementia (EPAD) Consortium; Fundació ACE Healthy Brain Initiative (FACEHBI) Study Group; BIOFACE Study Group. Oomens JE, et al. Among authors: orellana a. JAMA Netw Open. 2025 Jan 2;8(1):e2455571. doi: 10.1001/jamanetworkopen.2024.55571. JAMA Netw Open. 2025. PMID: 39841474 Free PMC article.
Depressive Symptoms and Amyloid Pathology.
Wiels WA, Oomens JE, Engelborghs S, Baeken C, von Arnim CAF, Boada M, Didic M, Dubois B, Fladby T, van der Flier WM, Frisoni GB, Fröhlich L, Gill KD, Grimmer T, Hildebrandt H, Hort J, Itoh Y, Iwatsubo T, Klimkowicz-Mrowiec A, Lee DY, Lleó A, Martinez-Lage P, de Mendonça A, Meyer PT, Kapaki EN, Parchi P, Pardini M, Parnetti L, Popp J, Rami L, Reiman EM, Rinne JO, Rodrigue KM, Sánchez-Juan P, Santana I, Sarazin M, Scarmeas N, Skoog I, Snyder PJ, Sperling RA, Villeneuve S, Wallin A, Wiltfang J, Zetterberg H, Ossenkoppele R, Verhey FRJ, Vos SJB, Visser PJ, Jansen WJ; Amyloid Biomarker Study group; Alzheimer’s Disease Neuroimaging Initiative (ADNI), the A4 Study group, Dominantly Inherited Alzheimer Network (DIAN), European Prevention of Alzheimer’s Dementia (EPAD) consortium, Fundació ACE Healthy Brain Initiative (FACEHBI), Harvard Aging Brain Stud; Alcolea D, Altomare D, Baiardi S, Baldeiras I, Bateman RJ, Blennow K, Bottlaender M, den Braber A, van Buchem MA, Byun MS, Cerman J, Chen K, Chipi E, Day GS, Drzezga A, Eckerström M, Ekblad LL, Epelbaum S, Förster S, Fortea J, Freund-Levi Y, Frings L, Guedj E, Hausner L, Hellwig S, Huey ED, Jiménez-Bonilla JF, Johnson KA, Juaristi AI, Kand… See abstract for full author list ➔ Wiels WA, et al. Among authors: orellana a. JAMA Psychiatry. 2025 Jan 22. doi: 10.1001/jamapsychiatry.2024.4305. Online ahead of print. JAMA Psychiatry. 2025. PMID: 39841452
Head-to-Head Comparison of Aptamer- and Antibody-Based Proteomic Platforms in Human Cerebrospinal Fluid Samples from a Real-World Memory Clinic Cohort.
Puerta R, Cano A, García-González P, García-Gutiérrez F, Capdevila M, de Rojas I, Olivé C, Blázquez-Folch J, Sotolongo-Grau O, Miguel A, Montrreal L, Martino-Adami P, Khan A, Orellana A, Sung YJ, Frikke-Schmidt R, Marchant N, Lambert JC, Rosende-Roca M, Alegret M, Fernández MV, Marquié M, Valero S, Tárraga L, Cruchaga C, Ramírez A, Boada M, Smets B, Cabrera-Socorro A, Ruiz A. Puerta R, et al. Among authors: orellana a. Int J Mol Sci. 2024 Dec 31;26(1):286. doi: 10.3390/ijms26010286. Int J Mol Sci. 2024. PMID: 39796148 Free PMC article.
Associations of plasma SMOC1 and soluble IL6RA levels with the progression from mild cognitive impairment to dementia.
Morató X, Puerta R, Cano A, Orellana A, de Rojas I, Capdevila M, Montrreal L, Rosende-Roca M, García-González P, Olivé C, García-Gutiérrez F, Blázquez J, Miguel A, Núñez-Llaves R, Pytel V, Alegret M, Fernández MV, Marquié M, Valero S, Cavazos JE, Mañes S, Boada M, Cabrera-Socorro A, Ruiz A. Morató X, et al. Among authors: orellana a. Brain Behav Immun Health. 2024 Nov 16;42:100899. doi: 10.1016/j.bbih.2024.100899. eCollection 2024 Dec. Brain Behav Immun Health. 2024. PMID: 39640195 Free PMC article.
Head-to-head comparison of tau PET tracers [18F]PI-2620 and [18F]RO948 in non-demented individuals with brain amyloid deposition: the TAU-PET FACEHBI cohort.
Tonietto M, Sotolongo-Grau O, Roé-Vellvé N, Bullich S, Tartari JP, Sanabria Á, García-Sánchez A, Borroni E, Galli C, Pérez-Martínez E, Castell-Conesa J, Roca I, Tárraga L, Ruiz A, Stephens AW, Boada M, Klein G, Marquié M; FACEHBI study group; AMYPAD consortium. Tonietto M, et al. Alzheimers Res Ther. 2024 Nov 28;16(1):257. doi: 10.1186/s13195-024-01622-5. Alzheimers Res Ther. 2024. PMID: 39605030 Free PMC article.
Amyloid deposition in adults with drug-resistant temporal lobe epilepsy.
Fonseca E, Lallana S, Ortega G, Cano A, Sarria-Estrada S, Pareto D, Quintana M, Lorenzo-Bosquet C, López-Maza S, Gifreu A, Campos-Fernández D, Abraira L, Santamarina E, Orellana A, Montrreal L, Puerta R, Aguilera N, Ramis M, de Rojas I, Ruiz A, Tárraga L, Rovira À, Marquié M, Boada M, Toledo M. Fonseca E, et al. Among authors: orellana a. Epilepsia. 2024 Dec;65(12):3664-3675. doi: 10.1111/epi.18142. Epub 2024 Oct 15. Epilepsia. 2024. PMID: 39403981
Clinical value of plasma pTau181 to predict Alzheimer's disease pathology in a large real-world cohort of a memory clinic.
Cano A, Capdevila M, Puerta R, Arranz J, Montrreal L, de Rojas I, García-González P, Olivé C, García-Gutiérrez F, Sotolongo-Grau O, Orellana A, Aguilera N, Ramis M, Rosende-Roca M, Lleó A, Fortea J, Tartari JP, Lafuente A, Vargas L, Pérez-Cordón A, Muñoz N, Sanabria Á, Alegret M, Morató X, Tárraga L, Fernández V, Marquié M, Valero S, Alcolea D, Boada M, Ruiz A. Cano A, et al. Among authors: orellana a. EBioMedicine. 2024 Oct;108:105345. doi: 10.1016/j.ebiom.2024.105345. Epub 2024 Sep 18. EBioMedicine. 2024. PMID: 39299003 Free PMC article.
Connecting genomic and proteomic signatures of amyloid burden in the brain.
Puerta R, de Rojas I, García-González P, Olivé C, Sotolongo-Grau O, García-Sánchez A, García-Gutiérrez F, Montrreal L, Pablo Tartari J, Sanabria Á, Pytel V, Lage C, Quintela I, Aguilera N, Rodriguez-Rodriguez E, Alarcón-Martín E, Orellana A, Pastor P, Pérez-Tur J, Piñol-Ripoll G, de Munian AL, García-Alberca JM, Royo JL, Bullido MJ, Álvarez V, Real LM, Anchuelo AC, Gómez-Garre D, Larrad MTM, Franco-Macías E, Mir P, Medina M, Sánchez-Valle R, Dols-Icardo O, Sáez ME, Carracedo Á, Tárraga L, Alegret M, Valero S, Marquié M, Boada M, Juan PS, Cavazos JE, Cabrera A, Cano A; Alzheimer’s Disease Neuroimaging Initiative.. Puerta R, et al. Among authors: orellana a. medRxiv [Preprint]. 2024 Sep 6:2024.09.06.24313124. doi: 10.1101/2024.09.06.24313124. medRxiv. 2024. PMID: 39281766 Free PMC article. Preprint.
Association of oxidative stress and inflammatory metabolites with Alzheimer's disease cerebrospinal fluid biomarkers in mild cognitive impairment.
Ahmad S, Yang W, Orellana A, Frölich L, de Rojas I, Cano A, Boada M, Hernández I, Hausner L, Harms AC, Bakker MHM, Cabrera-Socorro A, Amin N, Ramírez A, Ruiz A, Van Duijn CM, Hankemeier T. Ahmad S, et al. Among authors: orellana a. Alzheimers Res Ther. 2024 Jul 30;16(1):171. doi: 10.1186/s13195-024-01542-4. Alzheimers Res Ther. 2024. PMID: 39080778 Free PMC article.
Sex and aging signatures of proteomics in human cerebrospinal fluid identify distinct clusters linked to neurodegeneration.
Seo D, Lee CM, Apio C, Heo G, Timsina J, Kohlfeld P, Boada M, Orellana A, Fernandez MV, Ruiz A, Morris JC, Schindler SE, Park T, Cruchaga C, Sung YJ. Seo D, et al. Among authors: orellana a. medRxiv [Preprint]. 2024 Jun 19:2024.06.18.24309102. doi: 10.1101/2024.06.18.24309102. medRxiv. 2024. PMID: 38947020 Free PMC article. Preprint.
235 results