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Page 1
The microbe-derived short-chain fatty acids butyrate and propionate are associated with protection from chronic GVHD.
Markey KA, Schluter J, Gomes ALC, Littmann ER, Pickard AJ, Taylor BP, Giardina PA, Weber D, Dai A, Docampo MD, Armijo GK, Slingerland AE, Slingerland JB, Nichols KB, Brereton DG, Clurman AG, Ramos RJ, Rao A, Bush A, Bohannon L, Covington M, Lew MV, Rizzieri DA, Chao N, Maloy M, Cho C, Politikos I, Giralt S, Taur Y, Pamer EG, Holler E, Perales MA, Ponce DM, Devlin SM, Xavier J, Sung AD, Peled JU, Cross JR, van den Brink MRM. Markey KA, et al. Blood. 2020 Jul 2;136(1):130-136. doi: 10.1182/blood.2019003369. Blood. 2020. PMID: 32430495 Free PMC article.
Type I-IFNs control GVHD and GVL responses after transplantation.
Robb RJ, Kreijveld E, Kuns RD, Wilson YA, Olver SD, Don AL, Raffelt NC, De Weerd NA, Lineburg KE, Varelias A, Markey KA, Koyama M, Clouston AD, Hertzog PJ, Macdonald KP, Hill GR. Robb RJ, et al. Among authors: markey ka. Blood. 2011 Sep 22;118(12):3399-409. doi: 10.1182/blood-2010-12-325746. Epub 2011 Jun 30. Blood. 2011. PMID: 21719602 Free article.
Immune insufficiency during GVHD is due to defective antigen presentation within dendritic cell subsets.
Markey KA, Koyama M, Kuns RD, Lineburg KE, Wilson YA, Olver SD, Raffelt NC, Don AL, Varelias A, Robb RJ, Cheong M, Engwerda CR, Steptoe RJ, Ramshaw HS, Lopez AF, Vega-Ramos J, Lew AM, Villadangos JA, Hill GR, MacDonald KP. Markey KA, et al. Blood. 2012 Jun 14;119(24):5918-30. doi: 10.1182/blood-2011-12-398164. Epub 2012 Mar 13. Blood. 2012. PMID: 22415754 Free article.
Identification and expansion of highly suppressive CD8(+)FoxP3(+) regulatory T cells after experimental allogeneic bone marrow transplantation.
Robb RJ, Lineburg KE, Kuns RD, Wilson YA, Raffelt NC, Olver SD, Varelias A, Alexander KA, Teal BE, Sparwasser T, Hammerling GJ, Markey KA, Koyama M, Clouston AD, Engwerda CR, Hill GR, MacDonald KP. Robb RJ, et al. Among authors: markey ka. Blood. 2012 Jun 14;119(24):5898-908. doi: 10.1182/blood-2011-12-396119. Epub 2012 Apr 26. Blood. 2012. PMID: 22538855 Free article.
Lung parenchyma-derived IL-6 promotes IL-17A-dependent acute lung injury after allogeneic stem cell transplantation.
Varelias A, Gartlan KH, Kreijveld E, Olver SD, Lor M, Kuns RD, Lineburg KE, Teal BE, Raffelt NC, Cheong M, Alexander KA, Koyama M, Markey KA, Sturgeon E, Leach J, Reddy P, Kennedy GA, Yanik GA, Blazar BR, Tey SK, Clouston AD, MacDonald KP, Cooke KR, Hill GR. Varelias A, et al. Among authors: markey ka. Blood. 2015 Apr 9;125(15):2435-44. doi: 10.1182/blood-2014-07-590232. Epub 2015 Feb 11. Blood. 2015. PMID: 25673640 Free PMC article.
Tc17 cells are a proinflammatory, plastic lineage of pathogenic CD8+ T cells that induce GVHD without antileukemic effects.
Gartlan KH, Markey KA, Varelias A, Bunting MD, Koyama M, Kuns RD, Raffelt NC, Olver SD, Lineburg KE, Cheong M, Teal BE, Lor M, Comerford I, Teng MW, Smyth MJ, McCluskey J, Rossjohn J, Stockinger B, Boyle GM, Lane SW, Clouston AD, McColl SR, MacDonald KP, Hill GR. Gartlan KH, et al. Among authors: markey ka. Blood. 2015 Sep 24;126(13):1609-20. doi: 10.1182/blood-2015-01-622662. Epub 2015 Jul 23. Blood. 2015. PMID: 26206951 Free article.
Corruption of dendritic cell antigen presentation during acute GVHD leads to regulatory T-cell failure and chronic GVHD.
Leveque-El Mouttie L, Koyama M, Le Texier L, Markey KA, Cheong M, Kuns RD, Lineburg KE, Teal BE, Alexander KA, Clouston AD, Blazar BR, Hill GR, MacDonald KP. Leveque-El Mouttie L, et al. Among authors: markey ka. Blood. 2016 Aug 11;128(6):794-804. doi: 10.1182/blood-2015-11-680876. Epub 2016 Jun 23. Blood. 2016. PMID: 27338097 Free PMC article.
109 results