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Truncation of Pik3r1 causes severe insulin resistance uncoupled from obesity and dyslipidaemia by increased energy expenditure.
Kwok A, Zvetkova I, Virtue S, Luijten I, Huang-Doran I, Tomlinson P, Bulger DA, West J, Murfitt S, Griffin J, Alam R, Hart D, Knox R, Voshol P, Vidal-Puig A, Jensen J, O'Rahilly S, Semple RK. Kwok A, et al. Among authors: alam r. Mol Metab. 2020 Oct;40:101020. doi: 10.1016/j.molmet.2020.101020. Epub 2020 May 19. Mol Metab. 2020. PMID: 32439336 Free PMC article.
PI3Kδ hyper-activation promotes development of B cells that exacerbate Streptococcus pneumoniae infection in an antibody-independent manner.
Stark AK, Chandra A, Chakraborty K, Alam R, Carbonaro V, Clark J, Sriskantharajah S, Bradley G, Richter AG, Banham-Hall E, Clatworthy MR, Nejentsev S, Hamblin JN, Hessel EM, Condliffe AM, Okkenhaug K. Stark AK, et al. Among authors: alam r. Nat Commun. 2018 Aug 9;9(1):3174. doi: 10.1038/s41467-018-05674-8. Nat Commun. 2018. PMID: 30093657 Free PMC article.
Enzymatic epimerization of monoterpene indole alkaloids in Kratom.
McDonald A, Nakamura Y, Schotte C, Lau K, Alam R, Lopes AA, Buell CR, O'Connor S. McDonald A, et al. Among authors: alam r. bioRxiv [Preprint]. 2024 Dec 13:2024.12.13.628308. doi: 10.1101/2024.12.13.628308. bioRxiv. 2024. PMID: 39713415 Free PMC article. Preprint.
602 results