Lehr T - Search Results

1

A Comprehensive Whole-Body Physiologically Based Pharmacokinetic Drug-Drug-Gene Interaction Model of Metformin and Cimetidine in Healthy Adults and Renally Impaired Individuals.

Hanke N, Türk D, Selzer D, Ishiguro N, Ebner T, Wiebe S, Müller F, Stopfer P, Nock V, Lehr T. Hanke N, et al. Among authors: lehr t. Clin Pharmacokinet. 2020 Nov;59(11):1419-1431. doi: 10.1007/s40262-020-00896-w. Clin Pharmacokinet. 2020. PMID: 32449077 Free PMC article.

2

Problematic Internet Use among Adolescents 18 Months after the Onset of the COVID-19 Pandemic.

Paulus FW, Joas J, Gerstner I, Kühn A, Wenning M, Gehrke T, Burckhart H, Richter U, Nonnenmacher A, Zemlin M, Lücke T, Brinkmann F, Rothoeft T, Lehr T, Möhler E. Paulus FW, et al. Among authors: lehr t. Children (Basel). 2022 Nov 10;9(11):1724. doi: 10.3390/children9111724. Children (Basel). 2022. PMID: 36360452 Free PMC article.

3

A quantitative enterohepatic circulation model: development and evaluation with tesofensine and meloxicam.

Lehr T, Staab A, Tillmann C, Trommeshauser D, Schaefer HG, Kloft C. Lehr T, et al. Clin Pharmacokinet. 2009;48(8):529-42. doi: 10.2165/11313370-000000000-00000. Clin Pharmacokinet. 2009. PMID: 19705923 Clinical Trial.

4

Semi-mechanistic population pharmacokinetic drug-drug interaction modelling of a long half-life substrate and itraconazole.

Lehr T, Staab A, Trommeshauser D, Schaefer HG, Kloft C. Lehr T, et al. Clin Pharmacokinet. 2010;49(1):53-66. doi: 10.2165/11317210-000000000-00000. Clin Pharmacokinet. 2010. PMID: 20000889

5

Pharmacometric characterization of dabigatran hemodialysis.

Liesenfeld KH, Staab A, Härtter S, Formella S, Clemens A, Lehr T. Liesenfeld KH, et al. Among authors: lehr t. Clin Pharmacokinet. 2013 Jun;52(6):453-62. doi: 10.1007/s40262-013-0049-6. Clin Pharmacokinet. 2013. PMID: 23529813 Free PMC article. Clinical Trial.

6

Impact of Demographics, Organ Impairment, Disease, Formulation, and Food on the Pharmacokinetics of the Selective S1P₁ Receptor Modulator Ponesimod Based on 13 Clinical Studies.

Lott D, Lehr T, Dingemanse J, Krause A. Lott D, et al. Among authors: lehr t. Clin Pharmacokinet. 2017 Apr;56(4):395-408. doi: 10.1007/s40262-016-0446-8. Clin Pharmacokinet. 2017. PMID: 27638335

7

Clarithromycin, Midazolam, and Digoxin: Application of PBPK Modeling to Gain New Insights into Drug-Drug Interactions and Co-medication Regimens.

Moj D, Hanke N, Britz H, Frechen S, Kanacher T, Wendl T, Haefeli WE, Lehr T. Moj D, et al. Among authors: lehr t. AAPS J. 2017 Jan;19(1):298-312. doi: 10.1208/s12248-016-0009-9. Epub 2016 Nov 7. AAPS J. 2017. PMID: 27822600

8

Target-Mediated Drug Disposition Pharmacokinetic-Pharmacodynamic Model of Bosentan and Endothelin-1.

Volz AK, Krause A, Haefeli WE, Dingemanse J, Lehr T. Volz AK, et al. Among authors: lehr t. Clin Pharmacokinet. 2017 Dec;56(12):1499-1511. doi: 10.1007/s40262-017-0534-4. Clin Pharmacokinet. 2017. PMID: 28401480

9

A physiologically based pharmacokinetic (PBPK) parent-metabolite model of the chemotherapeutic zoptarelin doxorubicin-integration of in vitro results, Phase I and Phase II data and model application for drug-drug interaction potential analysis.

Hanke N, Teifel M, Moj D, Wojtyniak JG, Britz H, Aicher B, Sindermann H, Ammer N, Lehr T. Hanke N, et al. Among authors: lehr t. Cancer Chemother Pharmacol. 2018 Feb;81(2):291-304. doi: 10.1007/s00280-017-3495-2. Epub 2017 Dec 4. Cancer Chemother Pharmacol. 2018. PMID: 29204687 Clinical Trial.

10

Population nutrikinetics of green tea extract.

Scholl C, Lepper A, Lehr T, Hanke N, Schneider KL, Brockmöller J, Seufferlein T, Stingl JC. Scholl C, et al. Among authors: lehr t. PLoS One. 2018 Feb 21;13(2):e0193074. doi: 10.1371/journal.pone.0193074. eCollection 2018. PLoS One. 2018. PMID: 29466429 Free PMC article. Clinical Trial.

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