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Structure-Permeability Relationship of Semipeptidic Macrocycles-Understanding and Optimizing Passive Permeability and Efflux Ratio.
Le Roux A, Blaise É, Boudreault PL, Comeau C, Doucet A, Giarrusso M, Collin MP, Neubauer T, Kölling F, Göller AH, Seep L, Tshitenge DT, Wittwer M, Kullmann M, Hillisch A, Mittendorf J, Marsault E. Le Roux A, et al. Among authors: kullmann m. J Med Chem. 2020 Jul 9;63(13):6774-6783. doi: 10.1021/acs.jmedchem.0c00013. Epub 2020 May 26. J Med Chem. 2020. PMID: 32453569
Discovery of BAY 2413555, First Selective Positive Allosteric Modulator of the M2 Receptor to Restore Cardiac Autonomic Balance.
Vakalopoulos A, Basting D, Brechmann M, Teller H, Boultadakis Arapinis M, Straub A, Mittendorf J, Meininghaus M, Müller T, Nowak-Reppel K, Schäfer M, Wittwer M, Kullmann M, Terjung C, Lang D, Poethko T, Marquardt T, Freudenberger T, Mondritzki T, Hüser J, Heckmann M, Tinel H. Vakalopoulos A, et al. Among authors: kullmann m. J Med Chem. 2024 Nov 14;67(21):19165-19187. doi: 10.1021/acs.jmedchem.4c01590. Epub 2024 Oct 28. J Med Chem. 2024. PMID: 39463278
Transcutaneous glomerular filtration rate measurement in a canine animal model of chronic kidney disease.
Mondritzki T, Steinbach SML, Boehme P, Hoffmann J, Kullmann M, Schock-Kusch D, Vogel J, Kolkhof P, Sandner P, Bischoff E, Hüser J, Dinh W, Truebel H. Mondritzki T, et al. Among authors: kullmann m. J Pharmacol Toxicol Methods. 2018 Mar-Apr;90:7-12. doi: 10.1016/j.vascn.2017.10.009. Epub 2017 Oct 31. J Pharmacol Toxicol Methods. 2018. PMID: 29100965
Preclinical efficacy and pharmacokinetics of an RNA-encoded T cell-engaging bispecific antibody targeting human claudin 6.
Stadler CR, Ellinghaus U, Fischer L, Bähr-Mahmud H, Rao M, Lindemann C, Chaturvedi A, Scharf C, Biermann I, Hebich B, Malz A, Beresin G, Falck G, Häcker A, Houben A, Erdeljan M, Wolf K, Kullmann M, Chang P, Türeci Ö, Şahin U. Stadler CR, et al. Among authors: kullmann m. Sci Transl Med. 2024 May 22;16(748):eadl2720. doi: 10.1126/scitranslmed.adl2720. Epub 2024 May 22. Sci Transl Med. 2024. PMID: 38776391
Effects of Genetic Polymorphism in CYP2D6, CYP2C19, and the Organic Cation Transporter OCT1 on Amitriptyline Pharmacokinetics in Healthy Volunteers and Depressive Disorder Patients.
Matthaei J, Brockmöller J, Steimer W, Pischa K, Leucht S, Kullmann M, Jensen O, Ouethy T, Tzvetkov MV, Rafehi M. Matthaei J, et al. Among authors: kullmann m. Front Pharmacol. 2021 May 21;12:688950. doi: 10.3389/fphar.2021.688950. eCollection 2021. Front Pharmacol. 2021. PMID: 34093211 Free PMC article.
42 results