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Anoikis-resistant subpopulations of human osteosarcoma display significant chemoresistance and are sensitive to targeted epigenetic therapies predicted by expression profiling.
Foley JM, Scholten DJ 2nd, Monks NR, Cherba D, Monsma DJ, Davidson P, Dylewski D, Dykema K, Winn ME, Steensma MR. Foley JM, et al. Among authors: scholten dj 2nd. J Transl Med. 2015 Apr 2;13:110. doi: 10.1186/s12967-015-0466-4. J Transl Med. 2015. PMID: 25889105 Free PMC article.
Oculoectodermal syndrome is a mosaic RASopathy associated with KRAS alterations.
Peacock JD, Dykema KJ, Toriello HV, Mooney MR, Scholten DJ 2nd, Winn ME, Borgman A, Duesbery NS, Hiemenga JA, Liu C, Campbell S, Nickoloff BP, Williams BO, Steensma M. Peacock JD, et al. Among authors: scholten dj 2nd. Am J Med Genet A. 2015 Jul;167(7):1429-35. doi: 10.1002/ajmg.a.37048. Epub 2015 Mar 21. Am J Med Genet A. 2015. PMID: 25808193