O'Farrelly C - Search Results

1

Human PSC-Derived Hepatocytes Express Low Levels of Viral Pathogen Recognition Receptors, but Are Capable of Mounting an Effective Innate Immune Response.

Fischer L, Lucendo-Villarin B, Hay DC, O'Farrelly C. Fischer L, et al. Int J Mol Sci. 2020 May 28;21(11):3831. doi: 10.3390/ijms21113831. Int J Mol Sci. 2020. PMID: 32481600 Free PMC article.

2

Hepatitis C virus targets the interferon-α JAK/STAT pathway by promoting proteasomal degradation in immune cells and hepatocytes.

Stevenson NJ, Bourke NM, Ryan EJ, Binder M, Fanning L, Johnston JA, Hegarty JE, Long A, O'Farrelly C. Stevenson NJ, et al. FEBS Lett. 2013 May 21;587(10):1571-8. doi: 10.1016/j.febslet.2013.03.041. Epub 2013 Apr 12. FEBS Lett. 2013. PMID: 23587486 Free article.

3

Immune Cell Profiling of IFN-λ Response Shows pDCs Express Highest Level of IFN-λR1 and Are Directly Responsive via the JAK-STAT Pathway.

Kelly A, Robinson MW, Roche G, Biron CA, O'Farrelly C, Ryan EJ. Kelly A, et al. J Interferon Cytokine Res. 2016 Dec;36(12):671-680. doi: 10.1089/jir.2015.0169. Epub 2016 Sep 12. J Interferon Cytokine Res. 2016. PMID: 27617757 Free PMC article.

4

Designer human tissue: coming to a lab near you.

Hay DC, O'Farrelly C. Hay DC, et al. Philos Trans R Soc Lond B Biol Sci. 2018 Jul 5;373(1750):20170212. doi: 10.1098/rstb.2017.0212. Philos Trans R Soc Lond B Biol Sci. 2018. PMID: 29786548 Free PMC article.

5

Innate immunity in stem cell-derived hepatocytes.

Fischer L, Hay DC, O'Farrelly C. Fischer L, et al. Philos Trans R Soc Lond B Biol Sci. 2018 Jul 5;373(1750):20170220. doi: 10.1098/rstb.2017.0220. Philos Trans R Soc Lond B Biol Sci. 2018. PMID: 29786555 Free PMC article. Review.

6

Serum Free Production of Three-dimensional Human Hepatospheres from Pluripotent Stem Cells.

Lucendo-Villarin B, Rashidi H, Alhaque S, Fischer L, Meseguer-Ripolles J, Wang Y, O'Farrelly C, Themis M, Hay DC. Lucendo-Villarin B, et al. J Vis Exp. 2019 Jul 20;(149). doi: 10.3791/59965. J Vis Exp. 2019. PMID: 31380852

7

Hepatic Tumor Microenvironments and Effects on NK Cell Phenotype and Function.

Piñeiro Fernández J, Luddy KA, Harmon C, O'Farrelly C. Piñeiro Fernández J, et al. Int J Mol Sci. 2019 Aug 24;20(17):4131. doi: 10.3390/ijms20174131. Int J Mol Sci. 2019. PMID: 31450598 Free PMC article. Review.

8

Early interferon lambda production is induced by double-stranded RNA in iPS-derived hepatocyte-like cells.

Sularea VM, Sharma R, Hay DC, O'Farrelly C. Sularea VM, et al. Among authors: o farrelly c. Oxf Open Immunol. 2024 Jun 6;5(1):iqae004. doi: 10.1093/oxfimm/iqae004. eCollection 2024. Oxf Open Immunol. 2024. PMID: 39193476 Free PMC article.

9

Differential antimicrobial peptide gene expression patterns during early chicken embryological development.

Meade KG, Higgs R, Lloyd AT, Giles S, O'Farrelly C. Meade KG, et al. Dev Comp Immunol. 2009 Apr;33(4):516-24. doi: 10.1016/j.dci.2008.10.003. Epub 2008 Nov 11. Dev Comp Immunol. 2009. PMID: 19007808

10

The avian Toll-Like receptor pathway--subtle differences amidst general conformity.

Cormican P, Lloyd AT, Downing T, Connell SJ, Bradley D, O'Farrelly C. Cormican P, et al. Dev Comp Immunol. 2009 Sep;33(9):967-73. doi: 10.1016/j.dci.2009.04.001. Epub 2009 Apr 24. Dev Comp Immunol. 2009. PMID: 19539094

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