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Page 1
Analysis of Genetically Regulated Gene Expression Identifies a Prefrontal PTSD Gene, SNRNP35, Specific to Military Cohorts.
Huckins LM, Chatzinakos C, Breen MS, Hartmann J, Klengel T, da Silva Almeida AC, Dobbyn A, Girdhar K, Hoffman GE, Klengel C, Logue MW, Lori A, Maihofer AX, Morrison FG, Nguyen HT, Park Y, Ruderfer D, Sloofman LG, van Rooij SJH; PTSD Working Group of Psychiatric Genomics Consortium; Baker DG, Chen CY, Cox N, Duncan LE, Geyer MA, Glatt SJ, Im HK, Risbrough VB, Smoller JW, Stein DJ, Yehuda R, Liberzon I, Koenen KC, Jovanovic T, Kellis M, Miller MW, Bacanu SA, Nievergelt CM, Buxbaum JD, Sklar P, Ressler KJ, Stahl EA, Daskalakis NP. Huckins LM, et al. Among authors: klengel t, klengel c. Cell Rep. 2020 Jun 2;31(9):107716. doi: 10.1016/j.celrep.2020.107716. Cell Rep. 2020. PMID: 32492425 Free PMC article.
LINE1 insertions as a genomic risk factor for schizophrenia: Preliminary evidence from an affected family.
Guffanti G, Gaudi S, Klengel T, Fallon JH, Mangalam H, Madduri R, Rodriguez A, DeCrescenzo P, Glovienka E, Sobell J, Klengel C, Pato M, Ressler KJ, Pato C, Macciardi F. Guffanti G, et al. Among authors: klengel t, klengel c. Am J Med Genet B Neuropsychiatr Genet. 2016 Jun;171(4):534-45. doi: 10.1002/ajmg.b.32437. Epub 2016 Mar 16. Am J Med Genet B Neuropsychiatr Genet. 2016. PMID: 26990047
Mineralocorticoid receptors dampen glucocorticoid receptor sensitivity to stress via regulation of FKBP5.
Hartmann J, Bajaj T, Klengel C, Chatzinakos C, Ebert T, Dedic N, McCullough KM, Lardenoije R, Joëls M, Meijer OC, McCann KE, Dudek SM, Sarabdjitsingh RA, Daskalakis NP, Klengel T, Gassen NC, Schmidt MV, Ressler KJ. Hartmann J, et al. Among authors: klengel t, klengel c. Cell Rep. 2021 Jun 1;35(9):109185. doi: 10.1016/j.celrep.2021.109185. Cell Rep. 2021. PMID: 34077736 Free PMC article.
Blood levels of T-Cell Receptor Excision Circles (TRECs) provide an index of exposure to traumatic stress in mice and humans.
McCullough KM, Katrinli S, Hartmann J, Lori A, Klengel C, Missig G, Klengel T, Langford NA, Newman EL, Anderson KJ, Smith AK, Carroll FI, Ressler KJ, Carlezon WA Jr. McCullough KM, et al. Among authors: klengel c. Transl Psychiatry. 2022 Oct 3;12(1):423. doi: 10.1038/s41398-022-02159-7. Transl Psychiatry. 2022. PMID: 36192377 Free PMC article.
SKA2 enhances stress-related glucocorticoid receptor signaling through FKBP4-FKBP5 interactions in neurons.
Hartmann J, Klengel C, Dillmann LJ, Hisey EE, Hafner K, Shukla R, Soliva Estruch M, Bajaj T, Ebert T, Mabbott KG, Rostin L, Philipsen A, Carlezon WA Jr, Gisabella B, McCullumsmith RE, Vergis JM, Klengel T, Berretta S, Daskalakis NP, Pantazopoulos H, Gassen NC, Ressler KJ. Hartmann J, et al. Among authors: klengel c. Proc Natl Acad Sci U S A. 2024 Dec 24;121(52):e2417728121. doi: 10.1073/pnas.2417728121. Epub 2024 Dec 20. Proc Natl Acad Sci U S A. 2024. PMID: 39705315 Free PMC article.
Spermidine alleviates depression via control of the stress response.
Mackert S, Niemeyer C, Mecdad Y, Ebert T, Bajaj T, Durand S, Hofer SJ, Zellner A, Besteher B, Engelmann J, Gisabella B, Kempf V, Heckmann LA, Laakmann M, Newman EL, Sokn C, Heinz DE, Junglas E, Uribe-Marino A, Magnes C, Klengel C, Müller A, Opriessnig L, Meinitzer A, Lennarz M, Martin KMW, Albatarni R, Brockherde M, Lieb K, Rohner H, Stoffel-Wagner B, Philipsen A, Kuster B, Kölle M, Ressler KJ, Opel N, Schmidt MV, Pantazopoulos H, Müller MB, Kroemer G, Eisenberg T, Hartmann J, Madeo F, Gassen NC. Mackert S, et al. Among authors: klengel c. bioRxiv [Preprint]. 2024 Dec 7:2024.12.04.626625. doi: 10.1101/2024.12.04.626625. bioRxiv. 2024. PMID: 39677641 Free PMC article. Preprint.
A novel epigenetic clock for rhesus macaques unveils an association between early life adversity and epigenetic age acceleration.
Bronk G, Lardenoije R, Koolman L, Klengel C, Dan S, Howell BR, Morin EL, Meyer JS, Wilson ME, Ethun KF, Alvarado MC, Raper J, Bravo-Rivera H, Kenwood MM, Roseboom PH, Quirk GJ, Kalin NH, Binder EB, Sanchez MM, Klengel T. Bronk G, et al. Among authors: klengel c. bioRxiv [Preprint]. 2024 Oct 12:2024.10.08.617208. doi: 10.1101/2024.10.08.617208. bioRxiv. 2024. PMID: 39416061 Free PMC article. Preprint.
14 results