Sun Z - Search Results

1

Streptococcus pyogenes genes that promote pharyngitis in primates.

Zhu L, Olsen RJ, Beres SB, Saavedra MO, Kubiak SL, Cantu CC, Jenkins L, Waller AS, Sun Z, Palzkill T, Porter AR, DeLeo FR, Musser JM. Zhu L, et al. Among authors: sun z. JCI Insight. 2020 Jun 4;5(11):e137686. doi: 10.1172/jci.insight.137686. JCI Insight. 2020. PMID: 32493846 Free PMC article.

2

Deep Sequencing of Random Mutant Libraries Reveals the Active Site of the Narrow Specificity CphA Metallo-β-Lactamase is Fragile to Mutations.

Sun Z, Mehta SC, Adamski CJ, Gibbs RA, Palzkill T. Sun Z, et al. Sci Rep. 2016 Sep 12;6:33195. doi: 10.1038/srep33195. Sci Rep. 2016. PMID: 27616327 Free PMC article.

3

Synergistic effects of functionally distinct substitutions in β-lactamase variants shed light on the evolution of bacterial drug resistance.

Patel MP, Hu L, Brown CA, Sun Z, Adamski CJ, Stojanoski V, Sankaran B, Prasad BVV, Palzkill T. Patel MP, et al. Among authors: sun z. J Biol Chem. 2018 Nov 16;293(46):17971-17984. doi: 10.1074/jbc.RA118.003792. Epub 2018 Oct 1. J Biol Chem. 2018. PMID: 30275013 Free PMC article.

4

Differential active site requirements for NDM-1 β-lactamase hydrolysis of carbapenem versus penicillin and cephalosporin antibiotics.

Sun Z, Hu L, Sankaran B, Prasad BVV, Palzkill T. Sun Z, et al. Nat Commun. 2018 Oct 30;9(1):4524. doi: 10.1038/s41467-018-06839-1. Nat Commun. 2018. PMID: 30375382 Free PMC article.

5

Extensively Drug-Resistant Pseudomonas aeruginosa ST309 Harboring Tandem Guiana Extended Spectrum β-Lactamase Enzymes: A Newly Emerging Threat in the United States.

Khan A, Tran TT, Rios R, Hanson B, Shropshire WC, Sun Z, Diaz L, Dinh AQ, Wanger A, Ostrosky-Zeichner L, Palzkill T, Arias CA, Miller WR. Khan A, et al. Among authors: sun z. Open Forum Infect Dis. 2019 Jun 6;6(7):ofz273. doi: 10.1093/ofid/ofz273. eCollection 2019 Jul. Open Forum Infect Dis. 2019. PMID: 31281867 Free PMC article.

6

Antagonism between substitutions in β-lactamase explains a path not taken in the evolution of bacterial drug resistance.

Brown CA, Hu L, Sun Z, Patel MP, Singh S, Porter JR, Sankaran B, Prasad BVV, Bowman GR, Palzkill T. Brown CA, et al. Among authors: sun z. J Biol Chem. 2020 May 22;295(21):7376-7390. doi: 10.1074/jbc.RA119.012489. Epub 2020 Apr 16. J Biol Chem. 2020. PMID: 32299911 Free PMC article.

7

[No title available]

[No authors listed] [No authors listed] PMID: 33516358

8

Deep Mutational Scanning Reveals the Active-Site Sequence Requirements for the Colistin Antibiotic Resistance Enzyme MCR-1.

Sun Z, Palzkill T. Sun Z, et al. mBio. 2021 Dec 21;12(6):e0277621. doi: 10.1128/mBio.02776-21. Epub 2021 Nov 16. mBio. 2021. PMID: 34781730 Free PMC article.

9

Evaluation of Tebipenem Hydrolysis by β-Lactamases Prevalent in Complicated Urinary Tract Infections.

Sun Z, Su L, Cotroneo N, Critchley I, Pucci M, Jain A, Palzkill T. Sun Z, et al. Antimicrob Agents Chemother. 2022 May 17;66(5):e0239621. doi: 10.1128/aac.02396-21. Epub 2022 May 2. Antimicrob Agents Chemother. 2022. PMID: 35491852 Free PMC article.

10

Klebsiella pneumoniae carbapenemase variant 44 acquires ceftazidime-avibactam resistance by altering the conformation of active-site loops.

Sun Z, Lin H, Hu L, Neetu N, Sankaran B, Wang J, Prasad BVV, Palzkill T. Sun Z, et al. J Biol Chem. 2024 Jan;300(1):105493. doi: 10.1016/j.jbc.2023.105493. Epub 2023 Nov 23. J Biol Chem. 2024. PMID: 38000656 Free PMC article.

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