Holman CD - Search Results

1

Acyl-Coenzyme A Thioesterase 9 Traffics Mitochondrial Short-Chain Fatty Acids Toward De Novo Lipogenesis and Glucose Production in the Liver.

Steensels S, Qiao J, Zhang Y, Maner-Smith KM, Kika N, Holman CD, Corey KE, Bracken WC, Ortlund EA, Ersoy BA. Steensels S, et al. Among authors: holman cd. Hepatology. 2020 Sep;72(3):857-872. doi: 10.1002/hep.31409. Hepatology. 2020. PMID: 32498134

2

Preemptive Activation of the Integrated Stress Response Protects Mice From Diet-Induced Obesity and Insulin Resistance by Fibroblast Growth Factor 21 Induction.

Xu X, Krumm C, So JS, Bare CJ, Holman C, Gromada J, Cohen DE, Lee AH. Xu X, et al. Hepatology. 2018 Dec;68(6):2167-2181. doi: 10.1002/hep.30060. Epub 2018 Nov 5. Hepatology. 2018. PMID: 29698569 Free PMC article.

3

ChREBP-mediated up-regulation of Them1 coordinates thermogenesis with glycolysis and lipogenesis in response to chronic stress.

Xu X, Mendoza A, Krumm CS, Su S, Acuña M, Bare CJ, Holman CD, Cortopassi M, Nicholls HT, Dartigue V, Hollenberg AN, Lee AH, Hagen SJ, Cohen DE. Xu X, et al. Among authors: holman cd. Sci Signal. 2024 Dec 3;17(865):eadk7971. doi: 10.1126/scisignal.adk7971. Epub 2024 Dec 3. Sci Signal. 2024. PMID: 39626011

4

Inducible hepatic expression of CREBH mitigates diet-induced obesity, insulin resistance, and hepatic steatosis in mice.

Krumm CS, Xu X, Bare CJ, Holman CD, Kersten S, Dow LE, Lee AH, Cohen DE. Krumm CS, et al. Among authors: holman cd. J Biol Chem. 2021 Jul;297(1):100815. doi: 10.1016/j.jbc.2021.100815. Epub 2021 May 21. J Biol Chem. 2021. PMID: 34023388 Free PMC article.

5

Dissociation of Adaptive Thermogenesis from Glucose Homeostasis in Microbiome-Deficient Mice.

Krisko TI, Nicholls HT, Bare CJ, Holman CD, Putzel GG, Jansen RS, Sun N, Rhee KY, Banks AS, Cohen DE. Krisko TI, et al. Among authors: holman cd. Cell Metab. 2020 Mar 3;31(3):592-604.e9. doi: 10.1016/j.cmet.2020.01.012. Epub 2020 Feb 20. Cell Metab. 2020. PMID: 32084379 Free PMC article.

6

Nutritional Support from the Intestinal Microbiota Improves Hematopoietic Reconstitution after Bone Marrow Transplantation in Mice.

Staffas A, Burgos da Silva M, Slingerland AE, Lazrak A, Bare CJ, Holman CD, Docampo MD, Shono Y, Durham B, Pickard AJ, Cross JR, Stein-Thoeringer C, Velardi E, Tsai JJ, Jahn L, Jay H, Lieberman S, Smith OM, Pamer EG, Peled JU, Cohen DE, Jenq RR, van den Brink MRM. Staffas A, et al. Among authors: holman cd. Cell Host Microbe. 2018 Apr 11;23(4):447-457.e4. doi: 10.1016/j.chom.2018.03.002. Epub 2018 Mar 22. Cell Host Microbe. 2018. PMID: 29576480 Free PMC article.

7

Knockout of the X-linked Fgf13 in the hypothalamic paraventricular nucleus impairs sympathetic output to brown fat and causes obesity.

Sinden DS, Holman CD, Bare CJ, Sun X, Gade AR, Cohen DE, Pitt GS. Sinden DS, et al. Among authors: holman cd. FASEB J. 2019 Oct;33(10):11579-11594. doi: 10.1096/fj.201901178R. Epub 2019 Jul 24. FASEB J. 2019. PMID: 31339804 Free PMC article.

8

Blocking ActRIIB and restoring appetite reverses cachexia and improves survival in mice with lung cancer.

Queiroz AL, Dantas E, Ramsamooj S, Murthy A, Ahmed M, Zunica ERM, Liang RJ, Murphy J, Holman CD, Bare CJ, Ghahramani G, Wu Z, Cohen DE, Kirwan JP, Cantley LC, Axelrod CL, Goncalves MD. Queiroz AL, et al. Among authors: holman cd. Nat Commun. 2022 Aug 8;13(1):4633. doi: 10.1038/s41467-022-32135-0. Nat Commun. 2022. PMID: 35941104 Free PMC article.

9

Defining the lineage of thermogenic perivascular adipose tissue.

Angueira AR, Sakers AP, Holman CD, Cheng L, Arbocco MN, Shamsi F, Lynes MD, Shrestha R, Okada C, Batmanov K, Susztak K, Tseng YH, Liaw L, Seale P. Angueira AR, et al. Among authors: holman cd. Nat Metab. 2021 Apr;3(4):469-484. doi: 10.1038/s42255-021-00380-0. Epub 2021 Apr 12. Nat Metab. 2021. PMID: 33846639 Free PMC article.

10

Cardiac NAD⁺ depletion in mice promotes hypertrophic cardiomyopathy and arrhythmias prior to impaired bioenergetics.

Doan KV, Luongo TS, Ts'olo TT, Lee WD, Frederick DW, Mukherjee S, Adzika GK, Perry CE, Gaspar RB, Walker N, Blair MC, Bye N, Davis JG, Holman CD, Chu Q, Wang L, Rabinowitz JD, Kelly DP, Cappola TP, Margulies KB, Baur JA. Doan KV, et al. Among authors: holman cd. Nat Cardiovasc Res. 2024 Oct;3(10):1236-1248. doi: 10.1038/s44161-024-00542-9. Epub 2024 Sep 18. Nat Cardiovasc Res. 2024. PMID: 39294272

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