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127 results

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Page 1
Highly active rubiscos discovered by systematic interrogation of natural sequence diversity.
Davidi D, Shamshoum M, Guo Z, Bar-On YM, Prywes N, Oz A, Jablonska J, Flamholz A, Wernick DG, Antonovsky N, de Pins B, Shachar L, Hochhauser D, Peleg Y, Albeck S, Sharon I, Mueller-Cajar O, Milo R. Davidi D, et al. Among authors: hochhauser d. EMBO J. 2020 Sep 15;39(18):e104081. doi: 10.15252/embj.2019104081. Epub 2020 Jun 5. EMBO J. 2020. PMID: 32500941 Free PMC article.
An expanded arsenal of immune systems that protect bacteria from phages.
Millman A, Melamed S, Leavitt A, Doron S, Bernheim A, Hör J, Garb J, Bechon N, Brandis A, Lopatina A, Ofir G, Hochhauser D, Stokar-Avihail A, Tal N, Sharir S, Voichek M, Erez Z, Ferrer JLM, Dar D, Kacen A, Amitai G, Sorek R. Millman A, et al. Among authors: hochhauser d. Cell Host Microbe. 2022 Nov 9;30(11):1556-1569.e5. doi: 10.1016/j.chom.2022.09.017. Epub 2022 Oct 26. Cell Host Microbe. 2022. PMID: 36302390 Free article.
Homopolymer switches mediate adaptive mutability in mismatch repair-deficient colorectal cancer.
Kayhanian H, Cross W, van der Horst SEM, Barmpoutis P, Lakatos E, Caravagna G, Zapata L, Van Hoeck A, Middelkamp S, Litchfield K, Steele C, Waddingham W, Patel D, Milite S, Jin C, Baker AM, Alexander DC, Khan K, Hochhauser D, Novelli M, Werner B, van Boxtel R, Hageman JH, Buissant des Amorie JR, Linares J, Ligtenberg MJL, Nagtegaal ID, Laclé MM, Moons LMG, Brosens LAA, Pillay N, Sottoriva A, Graham TA, Rodriguez-Justo M, Shiu KK, Snippert HJG, Jansen M. Kayhanian H, et al. Among authors: hochhauser d. Nat Genet. 2024 Jul;56(7):1420-1433. doi: 10.1038/s41588-024-01777-9. Epub 2024 Jul 3. Nat Genet. 2024. PMID: 38956208 Free PMC article.
Copy number architectures define treatment-mediated selection of lethal prostate cancer clones.
Hasan AMM, Cremaschi P, Wetterskog D, Jayaram A, Wong SQ, Williams S, Pasam A, Trigos A, Trujillo B, Grist E, Friedrich S, Vainauskas O, Parry M, Ismail M, Devlies W, Wingate A, Linch M, Naceur-Lombardelli C; PEACE consortium; Swanton C, Jamal-Hanjani M, Lise S, Sandhu S, Attard G. Hasan AMM, et al. Nat Commun. 2023 Aug 10;14(1):4823. doi: 10.1038/s41467-023-40315-9. Nat Commun. 2023. PMID: 37563129 Free PMC article.
PANTHER: AZD8931, inhibitor of EGFR, ERBB2 and ERBB3 signalling, combined with FOLFIRI: a Phase I/II study to determine the importance of schedule and activity in colorectal cancer.
Propper DJ, Gao F, Saunders MP, Sarker D, Hartley JA, Spanswick VJ, Lowe HL, Hackett LD, Ng TT, Barber PR, Weitsman GE, Pearce S, White L, Lopes A, Forsyth S, Hochhauser D. Propper DJ, et al. Among authors: hochhauser d. Br J Cancer. 2023 Jan;128(2):245-254. doi: 10.1038/s41416-022-02015-x. Epub 2022 Nov 9. Br J Cancer. 2023. PMID: 36352028 Free PMC article. Clinical Trial.
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