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A Peroxodiiron(III/III) Intermediate Mediating Both N-Hydroxylation Steps in Biosynthesis of the N-Nitrosourea Pharmacophore of Streptozotocin by the Multi-domain Metalloenzyme SznF.
McBride MJ, Sil D, Ng TL, Crooke AM, Kenney GE, Tysoe CR, Zhang B, Balskus EP, Boal AK, Krebs C, Bollinger JM Jr. McBride MJ, et al. J Am Chem Soc. 2020 Jul 8;142(27):11818-11828. doi: 10.1021/jacs.0c03431. Epub 2020 Jun 24. J Am Chem Soc. 2020. PMID: 32511919 Free PMC article.
Substrate-Triggered μ-Peroxodiiron(III) Intermediate in the 4-Chloro-l-Lysine-Fragmenting Heme-Oxygenase-like Diiron Oxidase (HDO) BesC: Substrate Dissociation from, and C4 Targeting by, the Intermediate.
McBride MJ, Nair MA, Sil D, Slater JW, Neugebauer ME, Chang MCY, Boal AK, Krebs C, Bollinger JM Jr. McBride MJ, et al. Biochemistry. 2022 Apr 19;61(8):689-702. doi: 10.1021/acs.biochem.1c00774. Epub 2022 Apr 5. Biochemistry. 2022. PMID: 35380785 Free PMC article.
Proteo-metabolomics and patient tumor slice experiments point to amino acid centrality for rewired mitochondria in fibrolamellar carcinoma.
Long D Jr, Chan M, Han M, Kamdar Z, Ma RK, Tsai PY, Francisco AB, Barrow J, Shackelford DB, Yarchoan M, McBride MJ, Orre LM, Vacanti NM, Gujral TS, Sethupathy P. Long D Jr, et al. Among authors: mcbride mj. Cell Rep Med. 2024 Sep 17;5(9):101699. doi: 10.1016/j.xcrm.2024.101699. Epub 2024 Aug 28. Cell Rep Med. 2024. PMID: 39208801 Free PMC article.
114 results