Ng TL - Search Results

1

A Peroxodiiron(III/III) Intermediate Mediating Both N-Hydroxylation Steps in Biosynthesis of the N-Nitrosourea Pharmacophore of Streptozotocin by the Multi-domain Metalloenzyme SznF.

McBride MJ, Sil D, Ng TL, Crooke AM, Kenney GE, Tysoe CR, Zhang B, Balskus EP, Boal AK, Krebs C, Bollinger JM Jr. McBride MJ, et al. Among authors: ng tl. J Am Chem Soc. 2020 Jul 8;142(27):11818-11828. doi: 10.1021/jacs.0c03431. Epub 2020 Jun 24. J Am Chem Soc. 2020. PMID: 32511919 Free PMC article.

2

Heteroatom-Heteroatom Bond Formation in Natural Product Biosynthesis.

Waldman AJ, Ng TL, Wang P, Balskus EP. Waldman AJ, et al. Among authors: ng tl. Chem Rev. 2017 Apr 26;117(8):5784-5863. doi: 10.1021/acs.chemrev.6b00621. Epub 2017 Apr 4. Chem Rev. 2017. PMID: 28375000 Free PMC article. Review.

3

Glutamic acid is a carrier for hydrazine during the biosyntheses of fosfazinomycin and kinamycin.

Wang KA, Ng TL, Wang P, Huang Z, Balskus EP, van der Donk WA. Wang KA, et al. Among authors: ng tl. Nat Commun. 2018 Sep 11;9(1):3687. doi: 10.1038/s41467-018-06083-7. Nat Commun. 2018. PMID: 30206228 Free PMC article.

4

An N-nitrosating metalloenzyme constructs the pharmacophore of streptozotocin.

Ng TL, Rohac R, Mitchell AJ, Boal AK, Balskus EP. Ng TL, et al. Nature. 2019 Feb;566(7742):94-99. doi: 10.1038/s41586-019-0894-z. Epub 2019 Feb 6. Nature. 2019. PMID: 30728519 Free PMC article.

5

The l-Alanosine Gene Cluster Encodes a Pathway for Diazeniumdiolate Biosynthesis.

Ng TL, McCallum ME, Zheng CR, Wang JX, Wu KJY, Balskus EP. Ng TL, et al. Chembiochem. 2020 Apr 17;21(8):1155-1160. doi: 10.1002/cbic.201900565. Epub 2019 Dec 19. Chembiochem. 2020. PMID: 31643127 Free PMC article.

6

Discovery of the Azaserine Biosynthetic Pathway Uncovers a Biological Route for α-Diazoester Production.

Van Cura D, Ng TL, Huang J, Hager H, Hartwig JF, Keasling JD, Balskus EP. Van Cura D, et al. Among authors: ng tl. Angew Chem Int Ed Engl. 2023 Jul 10;62(28):e202304646. doi: 10.1002/anie.202304646. Epub 2023 May 31. Angew Chem Int Ed Engl. 2023. PMID: 37151182 Free PMC article.

7

Sustainable B₁₂-Dependent Dehalogenation of Organohalides in E. coli.

Ng TL, Silver PA. Ng TL, et al. ACS Chem Biol. 2024 Feb 16;19(2):380-391. doi: 10.1021/acschembio.3c00585. Epub 2024 Jan 22. ACS Chem Biol. 2024. PMID: 38254247

8

Theranostic cells: emerging clinical applications of synthetic biology.

McNerney MP, Doiron KE, Ng TL, Chang TZ, Silver PA. McNerney MP, et al. Among authors: ng tl. Nat Rev Genet. 2021 Nov;22(11):730-746. doi: 10.1038/s41576-021-00383-3. Epub 2021 Jul 7. Nat Rev Genet. 2021. PMID: 34234299 Free PMC article. Review.

9

Understanding the relationship between breast cancer, immune checkpoint inhibitors, and gut microbiota: a narrative review.

Hrubesz G, Leigh J, Ng TL. Hrubesz G, et al. Among authors: ng tl. Transl Breast Cancer Res. 2024 Oct 21;5:31. doi: 10.21037/tbcr-24-14. eCollection 2024. Transl Breast Cancer Res. 2024. PMID: 39534584 Free PMC article. Review.

10

NanoString nCounter-Based Assay for Detection of Fusion-Associated Salivary Gland Tumors.

Goytain A, Ng TL. Goytain A, et al. Among authors: ng tl. Head Neck Pathol. 2024 Oct 28;18(1):116. doi: 10.1007/s12105-024-01710-w. Head Neck Pathol. 2024. PMID: 39466450

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