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Upregulation of Multiple CD8+ T Cell Exhaustion Pathways Is Associated with Recurrent Ocular Herpes Simplex Virus Type 1 Infection.
Coulon PG, Roy S, Prakash S, Srivastava R, Dhanushkodi N, Salazar S, Amezquita C, Nguyen L, Vahed H, Nguyen AM, Warsi WR, Ye C, Carlos-Cruz EA, Mai UT, BenMohamed L. Coulon PG, et al. Among authors: srivastava r. J Immunol. 2020 Jul 15;205(2):454-468. doi: 10.4049/jimmunol.2000131. Epub 2020 Jun 15. J Immunol. 2020. PMID: 32540992 Free PMC article.
Phenotypic and functional characterization of herpes simplex virus glycoprotein B epitope-specific effector and memory CD8+ T cells from symptomatic and asymptomatic individuals with ocular herpes.
Khan AA, Srivastava R, Spencer D, Garg S, Fremgen D, Vahed H, Lopes PP, Pham TT, Hewett C, Kuang J, Ong N, Huang L, Scarfone VM, Nesburn AB, Wechsler SL, BenMohamed L. Khan AA, et al. Among authors: srivastava r. J Virol. 2015 Apr;89(7):3776-92. doi: 10.1128/JVI.03419-14. Epub 2015 Jan 21. J Virol. 2015. PMID: 25609800 Free PMC article.
HLA-A02:01-restricted epitopes identified from the herpes simplex virus tegument protein VP11/12 preferentially recall polyfunctional effector memory CD8+ T cells from seropositive asymptomatic individuals and protect humanized HLA-A*02:01 transgenic mice against ocular herpes.
Srivastava R, Khan AA, Spencer D, Vahed H, Lopes PP, Thai NT, Wang C, Pham TT, Huang J, Scarfone VM, Nesburn AB, Wechsler SL, BenMohamed L. Srivastava R, et al. J Immunol. 2015 Mar 1;194(5):2232-48. doi: 10.4049/jimmunol.1402606. Epub 2015 Jan 23. J Immunol. 2015. PMID: 25617474 Free PMC article.
Therapeutic immunization with a mixture of herpes simplex virus 1 glycoprotein D-derived “asymptomatic” human CD8+ T-cell epitopes decreases spontaneous ocular shedding in latently infected HLA transgenic rabbits: association with low frequency of local PD-1+ TIM-3+ CD8+ exhausted T cells.
Khan AA, Srivastava R, Chentoufi AA, Geertsema R, Thai NT, Dasgupta G, Osorio N, Kalantari M, Nesburn AB, Wechsler SL, BenMohamed L. Khan AA, et al. Among authors: srivastava r. J Virol. 2015 Jul;89(13):6619-32. doi: 10.1128/JVI.00788-15. J Virol. 2015. PMID: 25878105 Free PMC article.
Prior Corneal Scarification and Injection of Immune Serum are Not Required Before Ocular HSV-1 Infection for UV-B-Induced Virus Reactivation and Recurrent Herpetic Corneal Disease in Latently Infected Mice.
BenMohamed L, Osorio N, Khan AA, Srivastava R, Huang L, Krochmal JJ, Garcia JM, Simpson JL, Wechsler SL. BenMohamed L, et al. Among authors: srivastava r. Curr Eye Res. 2016 Jun;41(6):747-56. doi: 10.3109/02713683.2015.1061024. Epub 2015 Sep 23. Curr Eye Res. 2016. PMID: 26398722 Free PMC article.
The Herpes Simplex Virus Latency-Associated Transcript Gene Is Associated with a Broader Repertoire of Virus-Specific Exhausted CD8+ T Cells Retained within the Trigeminal Ganglia of Latently Infected HLA Transgenic Rabbits.
Srivastava R, Dervillez X, Khan AA, Chentoufi AA, Chilukuri S, Shukr N, Fazli Y, Ong NN, Afifi RE, Osorio N, Geertsema R, Nesburn AB, Wechsler SL, BenMohamed L. Srivastava R, et al. J Virol. 2016 Mar 28;90(8):3913-3928. doi: 10.1128/JVI.02450-15. Print 2016 Apr. J Virol. 2016. PMID: 26842468 Free PMC article.
3,150 results