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Page 1
Diethyldithiocarbamate encapsulation reduces toxicity and promotes leishmanicidal effect through apoptosis-like mechanism in promastigote and ROS production by macrophage.
Assolini JP, Tomiotto-Pellissier F, da Silva Bortoleti BT, Gonçalves MD, Sahd CS, Carloto ACM, Feuser PE, Cordeiro AP, Borghi SM, Verri WA Jr, Sayer C, Hermes de Araújo PH, Costa IN, Conchon-Costa I, Miranda-Sapla MM, Pavanelli WR. Assolini JP, et al. Among authors: da silva bortoleti bt. J Drug Target. 2020 Dec;28(10):1110-1123. doi: 10.1080/1061186X.2020.1783669. Epub 2020 Jun 30. J Drug Target. 2020. PMID: 32546016
Caryocar coriaceum extracts exert leishmanicidal effect acting in promastigote forms by apoptosis-like mechanism and intracellular amastigotes by Nrf2/HO-1/ferritin dependent response and iron depletion: Leishmanicidal effect of Caryocar coriaceum leaf exracts.
Tomiotto-Pellissier F, Alves DR, Miranda-Sapla MM, de Morais SM, Assolini JP, da Silva Bortoleti BT, Gonçalves MD, Cataneo AHD, Kian D, Madeira TB, Yamauchi LM, Nixdorf SL, Costa IN, Conchon-Costa I, Pavanelli WR. Tomiotto-Pellissier F, et al. Among authors: da silva bortoleti bt. Biomed Pharmacother. 2018 Feb;98:662-672. doi: 10.1016/j.biopha.2017.12.083. Epub 2018 Jan 4. Biomed Pharmacother. 2018. PMID: 29294453
4-nitrochalcone exerts leishmanicidal effect on L. amazonensis promastigotes and intracellular amastigotes, and the 4-nitrochalcone encapsulation in beeswax copaiba oil nanoparticles reduces macrophages cytotoxicity.
Assolini JP, da Silva TP, da Silva Bortoleti BT, Gonçalves MD, Tomiotto-Pellissier F, Sahd CS, Carloto ACM, Feuser PE, Cordeiro AP, Sayer C, Hermes de Araújo PH, Costa IN, Conchon-Costa I, Miranda-Sapla MM, Pavanelli WR. Assolini JP, et al. Among authors: da silva bortoleti bt. Eur J Pharmacol. 2020 Oct 5;884:173392. doi: 10.1016/j.ejphar.2020.173392. Epub 2020 Jul 28. Eur J Pharmacol. 2020. PMID: 32735985 Free article.
A 21st Century Evil: Immunopathology and New Therapies of COVID-19.
Silva TF, Tomiotto-Pellissier F, Sanfelice RA, Gonçalves MD, da Silva Bortoleti BT, Detoni MB, Rodrigues ACJ, Carloto ACM, Concato VM, Siqueira EDS, Costa IN, Pavanelli WR, Conchon-Costa I, Miranda-Sapla MM. Silva TF, et al. Among authors: da silva bortoleti bt. Front Immunol. 2020 Oct 27;11:562264. doi: 10.3389/fimmu.2020.562264. eCollection 2020. Front Immunol. 2020. PMID: 33193331 Free PMC article. Review.
Moringa oleifera extract promotes apoptosis-like death in Toxoplasma gondii tachyzoites in vitro.
Nishi L, Sanfelice RADS, da Silva Bortoleti BT, Tomiotto-Pellissier F, Silva TF, Evangelista FF, Lazarin-Bidóia D, Costa IN, Pavanelli WR, Conchon Costa I, Baptista ATA, Bergamasco R, Falavigna-Guilherme AL. Nishi L, et al. Among authors: da silva bortoleti bt. Parasitology. 2021 Oct;148(12):1447-1457. doi: 10.1017/S0031182021001086. Epub 2021 Jun 30. Parasitology. 2021. PMID: 34187608 Free PMC article.
Recent Advances in Biotransformation by Cunninghamella Species.
Gonçalves MD, Tomiotto-Pellissier F, de Matos RLN, Assolini JP, da Silva Bortoleti BT, Concato VM, Silva TF, Rafael JA, Pavanelli WR, Conchon-Costa I, Arakawa NS. Gonçalves MD, et al. Among authors: da silva bortoleti bt. Curr Drug Metab. 2021;22(13):1035-1064. doi: 10.2174/1389200222666211126100023. Curr Drug Metab. 2021. PMID: 34825868 Review.
Biogenic silver nanoparticles (AgNp-Bio) restore testosterone levels and increase TNF-α and IL-6 in Leydig cells infected with Toxoplasma gondii.
Semedo SSL, da Silva Sanfelice RA, Tomiotto-Pellissier F, Silva TF, da Silva Bortoleti BT, de Oliveira GC, de Lion Siervo GEM, Bosqui LR, Lazarin-Bidói D, Conchon-Costa I, de Barros LD, Garcia JL, Nakazato G, Pavanelli WR, Fernandes GSA, da Costa IN. Semedo SSL, et al. Among authors: da silva bortoleti bt. Exp Parasitol. 2022 Oct;241:108343. doi: 10.1016/j.exppara.2022.108343. Epub 2022 Aug 6. Exp Parasitol. 2022. PMID: 35944696 Free article.
Synergistic Antileishmanial Effect of Oregano Essential Oil and Silver Nanoparticles: Mechanisms of Action on Leishmania amazonensis.
Alves AB, da Silva Bortoleti BT, Tomiotto-Pellissier F, Ganaza AFM, Gonçalves MD, Carloto ACM, Rodrigues ACJ, Silva TF, Nakazato G, Kobayashi RKT, Lazarin-Bidóia D, Miranda-Sapla MM, Costa IN, Pavanelli WR, Conchon-Costa I. Alves AB, et al. Among authors: da silva bortoleti bt. Pathogens. 2023 Apr 29;12(5):660. doi: 10.3390/pathogens12050660. Pathogens. 2023. PMID: 37242330 Free PMC article.
Effect of a thiohydantoin salt derived from l-Arginine on Leishmania amazonensis and infected cells: Insights from biological effects to molecular docking interactions.
da Silva Bortoleti BT, Camargo PG, Gonçalves MD, Tomiotto-Pellissier F, Silva TF, Concato VM, Detoni MB, Bidóia DL, da Silva Lima CH, Rodrigues CR, Bispo MLF, de Macedo FC Jr, Conchon-Costa I, Miranda-Sapla MM, Wowk PF, Pavanelli WR. da Silva Bortoleti BT, et al. Chem Biol Interact. 2024 Nov 1;403:111216. doi: 10.1016/j.cbi.2024.111216. Epub 2024 Aug 31. Chem Biol Interact. 2024. PMID: 39218371
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