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Page 1
Triarylpyridine Compounds and Chloroquine Act in Concert to Trigger Lysosomal Membrane Permeabilization and Cell Death in Cancer Cells.
Beauvarlet J, Nath Das R, Alvarez-Valadez K, Martins I, Muller A, Darbo E, Richard E, Soubeyran P, Kroemer G, Guillon J, Mergny JL, Djavaheri-Mergny M. Beauvarlet J, et al. Among authors: mergny jl. Cancers (Basel). 2020 Jun 18;12(6):1621. doi: 10.3390/cancers12061621. Cancers (Basel). 2020. PMID: 32570977 Free PMC article.
Ultraviolet-A induces activation of AP-1 in cultured human keratinocytes.
Djavaheri-Mergny M, Mergny JL, Bertrand F, Santus R, Mazière C, Dubertret L, Mazière JC. Djavaheri-Mergny M, et al. Among authors: mergny jl. FEBS Lett. 1996 Apr 8;384(1):92-6. doi: 10.1016/0014-5793(96)00294-3. FEBS Lett. 1996. PMID: 8797811 Free article.
Design, Synthesis, and Evaluation of 2,9-Bis[(substituted-aminomethyl)phenyl]-1,10-phenanthroline Derivatives as G-Quadruplex Ligands.
Gueddouda NM, Hurtado MR, Moreau S, Ronga L, Das RN, Savrimoutou S, Rubio S, Marchand A, Mendoza O, Marchivie M, Elmi L, Chansavang A, Desplat V, Gabelica V, Bourdoncle A, Mergny JL, Guillon J. Gueddouda NM, et al. Among authors: mergny jl. ChemMedChem. 2017 Jan 20;12(2):146-160. doi: 10.1002/cmdc.201600511. Epub 2017 Jan 3. ChemMedChem. 2017. PMID: 27917615 Free article.
Design, synthesis, and antiprotozoal evaluation of new 2,9-bis[(substituted-aminomethyl)phenyl]-1,10-phenanthroline derivatives.
Guillon J, Cohen A, Das RN, Boudot C, Gueddouda NM, Moreau S, Ronga L, Savrimoutou S, Basmaciyan L, Tisnerat C, Mestanier S, Rubio S, Amaziane S, Dassonville-Klimpt A, Azas N, Courtioux B, Mergny JL, Mullié C, Sonnet P. Guillon J, et al. Among authors: mergny jl. Chem Biol Drug Des. 2018 May;91(5):974-995. doi: 10.1111/cbdd.13164. Epub 2018 Jan 17. Chem Biol Drug Des. 2018. PMID: 29266861
Modulation of the ATM/autophagy pathway by a G-quadruplex ligand tips the balance between senescence and apoptosis in cancer cells.
Beauvarlet J, Bensadoun P, Darbo E, Labrunie G, Rousseau B, Richard E, Draskovic I, Londono-Vallejo A, Dupuy JW, Nath Das R, Guédin A, Robert G, Orange F, Croce S, Valesco V, Soubeyran P, Ryan KM, Mergny JL, Djavaheri-Mergny M. Beauvarlet J, et al. Among authors: mergny jl. Nucleic Acids Res. 2019 Apr 8;47(6):2739-2756. doi: 10.1093/nar/gkz095. Nucleic Acids Res. 2019. PMID: 30759257 Free PMC article.
Design, synthesis, and antiproliferative effect of 2,9-bis[4-(pyridinylalkylaminomethyl)phenyl]-1,10-phenanthroline derivatives on human leukemic cells by targeting G-quadruplex.
Guillon J, Denevault-Sabourin C, Chevret E, Brachet-Botineau M, Milano V, Guédin-Beaurepaire A, Moreau S, Ronga L, Savrimoutou S, Rubio S, Ferrer J, Lamarche J, Mergny JL, Viaud-Massuard MC, Ranz M, Largy E, Gabelica V, Rosu F, Gouilleux F, Desplat V. Guillon J, et al. Among authors: mergny jl. Arch Pharm (Weinheim). 2021 Aug;354(8):e2000450. doi: 10.1002/ardp.202000450. Epub 2021 Apr 14. Arch Pharm (Weinheim). 2021. PMID: 33852185
G-quadruplex ligands as potent regulators of lysosomes.
Ferret L, Alvarez-Valadez K, Rivière J, Muller A, Bohálová N, Yu L, Guittat L, Brázda V, Kroemer G, Mergny JL, Djavaheri-Mergny M. Ferret L, et al. Among authors: mergny jl. Autophagy. 2023 Jul;19(7):1901-1915. doi: 10.1080/15548627.2023.2170071. Epub 2023 Feb 5. Autophagy. 2023. PMID: 36740766 Free PMC article.
321 results