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Use of Patient Health Records to Quantify Drug-Related Pro-arrhythmic Risk.
Davies MR, Martinec M, Walls R, Schwarz R, Mirams GR, Wang K, Steiner G, Surinach A, Flores C, Lavé T, Singer T, Polonchuk L. Davies MR, et al. Among authors: wang k. Cell Rep Med. 2020 Aug 25;1(5):100076. doi: 10.1016/j.xcrm.2020.100076. eCollection 2020 Aug 25. Cell Rep Med. 2020. PMID: 33205069 Free PMC article.
Human ex-vivo action potential model for pro-arrhythmia risk assessment.
Page G, Ratchada P, Miron Y, Steiner G, Ghetti A, Miller PE, Reynolds JA, Wang K, Greiter-Wilke A, Polonchuk L, Traebert M, Gintant GA, Abi-Gerges N. Page G, et al. Among authors: wang k. J Pharmacol Toxicol Methods. 2016 Sep-Oct;81:183-95. doi: 10.1016/j.vascn.2016.05.016. Epub 2016 May 25. J Pharmacol Toxicol Methods. 2016. PMID: 27235787 Free PMC article.
Rapid Characterization of hERG Channel Kinetics II: Temperature Dependence.
Lei CL, Clerx M, Beattie KA, Melgari D, Hancox JC, Gavaghan DJ, Polonchuk L, Wang K, Mirams GR. Lei CL, et al. Among authors: wang k. Biophys J. 2019 Dec 17;117(12):2455-2470. doi: 10.1016/j.bpj.2019.07.030. Epub 2019 Jul 25. Biophys J. 2019. PMID: 31451180 Free PMC article.
Multiscale modelling of drug mechanism and safety.
Zhang JD, Sach-Peltason L, Kramer C, Wang K, Ebeling M. Zhang JD, et al. Among authors: wang k. Drug Discov Today. 2020 Mar;25(3):519-534. doi: 10.1016/j.drudis.2019.12.009. Epub 2019 Dec 30. Drug Discov Today. 2020. PMID: 31899257 Free article. Review.
Translating pharmacology models effectively to predict therapeutic benefit.
Dudal S, Bissantz C, Caruso A, David-Pierson P, Driessen W, Koller E, Krippendorff BF, Lechmann M, Olivares-Morales A, Paehler A, Rynn C, Türck D, Van De Vyver A, Wang K, Winther L. Dudal S, et al. Among authors: wang k. Drug Discov Today. 2022 Jun;27(6):1604-1621. doi: 10.1016/j.drudis.2022.03.009. Epub 2022 Mar 15. Drug Discov Today. 2022. PMID: 35304340 Free article. Review.
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