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Identification and genomic analysis of pedigrees with exceptional longevity identifies candidate rare variants.
Miller JB, Ward E, Staley LA, Stevens J, Teerlink CC, Tavana JP, Cloward M, Page M, Dayton L; Alzheimer's Disease Genetics Consortium; Cannon-Albright LA, Kauwe JSK. Miller JB, et al. Among authors: page m. Neurobiol Dis. 2020 Sep;143:104972. doi: 10.1016/j.nbd.2020.104972. Epub 2020 Jun 21. Neurobiol Dis. 2020. PMID: 32574725 Free PMC article.
Analysis of high-risk pedigrees identifies 11 candidate variants for Alzheimer's disease.
Teerlink CC, Miller JB, Vance EL, Staley LA, Stevens J, Tavana JP, Cloward ME, Page ML, Dayton L; Alzheimer's Disease Genetics Consortium; Cannon-Albright LA, Kauwe JSK. Teerlink CC, et al. Alzheimers Dement. 2022 Feb;18(2):307-317. doi: 10.1002/alz.12397. Epub 2021 Jun 20. Alzheimers Dement. 2022. PMID: 34151536 Free PMC article.
Mapping medically relevant RNA isoform diversity in the aged human frontal cortex with deep long-read RNA-seq.
Aguzzoli Heberle B, Brandon JA, Page ML, Nations KA, Dikobe KI, White BJ, Gordon LA, Fox GA, Wadsworth ME, Doyle PH, Williams BA, Fox EJ, Shantaraman A, Ryten M, Goodwin S, Ghiban E, Wappel R, Mavruk-Eskipehlivan S, Miller JB, Seyfried NT, Nelson PT, Fryer JD, Ebbert MTW. Aguzzoli Heberle B, et al. Among authors: page ml. Nat Biotechnol. 2024 May 22. doi: 10.1038/s41587-024-02245-9. Online ahead of print. Nat Biotechnol. 2024. PMID: 38778214
Using deep long-read RNAseq in Alzheimer's disease brain to assess medical relevance of RNA isoform diversity.
Heberle BA, Brandon JA, Page ML, Nations KA, Dikobe KI, White BJ, Gordon LA, Fox GA, Wadsworth ME, Doyle PH, Williams BA, Fox EJ, Shantaraman A, Ryten M, Goodwin S, Ghiban E, Wappel R, Mavruk-Eskipehlivan S, Miller JB, Seyfried NT, Nelson PT, Fryer JD, Ebbert MTW. Heberle BA, et al. Among authors: page ml. bioRxiv [Preprint]. 2023 Dec 11:2023.08.06.552162. doi: 10.1101/2023.08.06.552162. bioRxiv. 2023. Update in: Nat Biotechnol. 2024 May 22. doi: 10.1038/s41587-024-02245-9 PMID: 37609156 Free PMC article. Updated. Preprint.
GWAS of multiple neuropathology endophenotypes identifies new risk loci and provides insights into the genetic risk of dementia.
Shade LMP, Katsumata Y, Abner EL, Aung KZ, Claas SA, Qiao Q, Heberle BA, Brandon JA, Page ML, Hohman TJ, Mukherjee S, Mayeux RP, Farrer LA, Schellenberg GD, Haines JL, Kukull WA, Nho K, Saykin AJ, Bennett DA, Schneider JA; National Alzheimer’s Coordinating Center; Ebbert MTW, Nelson PT, Fardo DW. Shade LMP, et al. Among authors: page ml. Nat Genet. 2024 Nov;56(11):2407-2421. doi: 10.1038/s41588-024-01939-9. Epub 2024 Oct 8. Nat Genet. 2024. PMID: 39379761 Free PMC article.
1,717 results