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First Clinical Use of Lenzilumab to Neutralize GM-CSF in Patients with Severe COVID-19 Pneumonia.
Temesgen Z, Assi M, Vergidis P, Rizza SA, Bauer PR, Pickering BW, Razonable RR, Libertin CR, Burger CD, Orenstein R, Vargas HE, Varatharaj Palraj BR, Dababneh AS, Chappell G, Chappell D, Ahmed O, Sakemura R, Durrant C, Kenderian SS, Badley A. Temesgen Z, et al. Among authors: ahmed o. medRxiv [Preprint]. 2020 Jun 14:2020.06.08.20125369. doi: 10.1101/2020.06.08.20125369. medRxiv. 2020. Update in: Mayo Clin Proc. 2020 Nov;95(11):2382-2394. doi: 10.1016/j.mayocp.2020.08.038 PMID: 32587983 Free PMC article. Updated. Preprint.
GM-CSF Neutralization With Lenzilumab in Severe COVID-19 Pneumonia: A Case-Cohort Study.
Temesgen Z, Assi M, Shweta FNU, Vergidis P, Rizza SA, Bauer PR, Pickering BW, Razonable RR, Libertin CR, Burger CD, Orenstein R, Vargas HE, Palraj R, Dababneh AS, Chappell G, Chappell D, Ahmed O, Sakemura R, Durrant C, Kenderian SS, Badley AD. Temesgen Z, et al. Among authors: ahmed o. Mayo Clin Proc. 2020 Nov;95(11):2382-2394. doi: 10.1016/j.mayocp.2020.08.038. Epub 2020 Sep 3. Mayo Clin Proc. 2020. PMID: 33153629 Free PMC article.
Lenzilumab in hospitalised patients with COVID-19 pneumonia (LIVE-AIR): a phase 3, randomised, placebo-controlled trial.
Temesgen Z, Burger CD, Baker J, Polk C, Libertin CR, Kelley CF, Marconi VC, Orenstein R, Catterson VM, Aronstein WS, Durrant C, Chappell D, Ahmed O, Chappell G, Badley AD; LIVE-AIR Study Group. Temesgen Z, et al. Among authors: ahmed o. Lancet Respir Med. 2022 Mar;10(3):237-246. doi: 10.1016/S2213-2600(21)00494-X. Epub 2021 Dec 1. Lancet Respir Med. 2022. PMID: 34863332 Free PMC article. Clinical Trial.
C reactive protein utilisation, a biomarker for early COVID-19 treatment, improves lenzilumab efficacy: results from the randomised phase 3 'LIVE-AIR' trial.
Temesgen Z, Kelley CF, Cerasoli F, Kilcoyne A, Chappell D, Durrant C, Ahmed O, Chappell G, Catterson V, Polk C, Badley A, Marconi VC; LIVE-AIR Study Group. Temesgen Z, et al. Among authors: ahmed o. Thorax. 2023 Jun;78(6):606-616. doi: 10.1136/thoraxjnl-2022-218744. Epub 2022 Jul 6. Thorax. 2023. PMID: 35793833 Free PMC article. Clinical Trial.
GM-CSF inhibition reduces cytokine release syndrome and neuroinflammation but enhances CAR-T cell function in xenografts.
Sterner RM, Sakemura R, Cox MJ, Yang N, Khadka RH, Forsman CL, Hansen MJ, Jin F, Ayasoufi K, Hefazi M, Schick KJ, Walters DK, Ahmed O, Chappell D, Sahmoud T, Durrant C, Nevala WK, Patnaik MM, Pease LR, Hedin KE, Kay NE, Johnson AJ, Kenderian SS. Sterner RM, et al. Among authors: ahmed o. Blood. 2019 Feb 14;133(7):697-709. doi: 10.1182/blood-2018-10-881722. Epub 2018 Nov 21. Blood. 2019. PMID: 30463995 Free PMC article.
GM-CSF disruption in CART cells modulates T cell activation and enhances CART cell anti-tumor activity.
Cox MJ, Manriquez Roman C, Tapper EE, Siegler EL, Chappell D, Durrant C, Ahmed O, Sinha S, Mwangi R, Scott NS, Hefazi M, Schick KJ, Horvei P, Ruff MW, Can I, Adada M, Bezerra E, Kankeu Fonkoua LA, Parikh SA, Kay NE, Sakemura R, Kenderian SS. Cox MJ, et al. Among authors: ahmed o. Leukemia. 2022 Jun;36(6):1635-1645. doi: 10.1038/s41375-022-01572-7. Epub 2022 Apr 19. Leukemia. 2022. PMID: 35440691 Free PMC article.
Correction: Alhakamy et al. Green Nanoemulsion Stabilized by In Situ Self-Assembled Natural Oil/Native Cyclodextrin Complexes: An Eco-Friendly Approach for Enhancing Anticancer Activity of Costunolide against Lung Cancer Cells. Pharmaceutics 2022, 14, 227.
Alhakamy NA, Badr-Eldin SM, Ahmed OAA, Aldawsari HM, Okbazghi SZ, Alfaleh MA, Abdulaal WH, Neamatallah T, Al-Hejaili OD, Fahmy UA. Alhakamy NA, et al. Among authors: ahmed oaa. Pharmaceutics. 2025 Jan 14;17(1):107. doi: 10.3390/pharmaceutics17010107. Pharmaceutics. 2025. PMID: 39861788 Free PMC article.
Utility of Hybrid Angio-CT in Interventional Radiology: Case-Based Examples.
Rivera Rodríguez DM, Goyal P, Varadhan AK, Kesavadas T, Nijhawan K, Sato KT, Ungchusri E, Funaki B, Golzarian J, Salem R, Mouli SK, Ahmed O. Rivera Rodríguez DM, et al. Among authors: ahmed o. J Vasc Interv Radiol. 2025 Jan 21:S1051-0443(25)00044-2. doi: 10.1016/j.jvir.2025.01.032. Online ahead of print. J Vasc Interv Radiol. 2025. PMID: 39848321 Review.
1,407 results