Insigne KD - Search Results

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Dissection of c-AMP Response Element Architecture by Using Genomic and Episomal Massively Parallel Reporter Assays.

Davis JE, Insigne KD, Jones EM, Hastings QA, Boldridge WC, Kosuri S. Davis JE, et al. Among authors: insigne kd. Cell Syst. 2020 Jul 22;11(1):75-85.e7. doi: 10.1016/j.cels.2020.05.011. Epub 2020 Jun 29. Cell Syst. 2020. PMID: 32603702 Free article.

Systematic Dissection of Sequence Elements Controlling σ70 Promoters Using a Genomically Encoded Multiplexed Reporter Assay in Escherichia coli.

Urtecho G, Tripp AD, Insigne KD, Kim H, Kosuri S. Urtecho G, et al. Among authors: insigne kd. Biochemistry. 2019 Mar 19;58(11):1539-1551. doi: 10.1021/acs.biochem.7b01069. Epub 2018 Dec 21. Biochemistry. 2019. PMID: 29388765 Free PMC article.

Multiplexed characterization of rationally designed promoter architectures deconstructs combinatorial logic for IPTG-inducible systems.

Yu TC, Liu WL, Brinck MS, Davis JE, Shek J, Bower G, Einav T, Insigne KD, Phillips R, Kosuri S, Urtecho G. Yu TC, et al. Among authors: insigne kd. Nat Commun. 2021 Jan 12;12(1):325. doi: 10.1038/s41467-020-20094-3. Nat Commun. 2021. PMID: 33436562 Free PMC article.

A Multiplexed Assay for Exon Recognition Reveals that an Unappreciated Fraction of Rare Genetic Variants Cause Large-Effect Splicing Disruptions.

Chong R, Insigne KD, Yao D, Burghard CP, Wang J, Hsiao YE, Jones EM, Goodman DB, Xiao X, Kosuri S. Chong R, et al. Among authors: insigne kd. Mol Cell. 2019 Jan 3;73(1):183-194.e8. doi: 10.1016/j.molcel.2018.10.037. Epub 2018 Nov 29. Mol Cell. 2019. PMID: 30503770 Free PMC article.

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