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Signature-based approaches for informed drug repurposing: targeting CNS disorders.
Shukla R, Henkel ND, Alganem K, Hamoud AR, Reigle J, Alnafisah RS, Eby HM, Imami AS, Creeden JF, Miruzzi SA, Meller J, Mccullumsmith RE. Shukla R, et al. Among authors: miruzzi sa. Neuropsychopharmacology. 2021 Jan;46(1):116-130. doi: 10.1038/s41386-020-0752-6. Epub 2020 Jun 30. Neuropsychopharmacology. 2021. PMID: 32604402 Free PMC article. Review.
Bilirubin remodels murine white adipose tissue by reshaping mitochondrial activity and the coregulator profile of peroxisome proliferator-activated receptor α.
Gordon DM, Neifer KL, Hamoud AA, Hawk CF, Nestor-Kalinoski AL, Miruzzi SA, Morran MP, Adeosun SO, Sarver JG, Erhardt PW, McCullumsmith RE, Stec DE, Hinds TD Jr. Gordon DM, et al. Among authors: miruzzi sa. J Biol Chem. 2020 Jul 17;295(29):9804-9822. doi: 10.1074/jbc.RA120.013700. Epub 2020 May 13. J Biol Chem. 2020. PMID: 32404366 Free PMC article.