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Pharmacological inhibition of lysine-specific demethylase 1 (LSD1) induces global transcriptional deregulation and ultrastructural alterations that impair viability in Schistosoma mansoni.
Coutinho Carneiro V, de Abreu da Silva IC, Amaral MS, Pereira ASA, Silveira GO, Pires DDS, Verjovski-Almeida S, Dekker FJ, Rotili D, Mai A, Lopes-Torres EJ, Robaa D, Sippl W, Pierce RJ, Borrello MT, Ganesan A, Lancelot J, Thiengo S, Fernandez MA, Vicentino ARR, Mourão MM, Coelho FS, Fantappié MR. Coutinho Carneiro V, et al. Among authors: pires dds. PLoS Negl Trop Dis. 2020 Jul 1;14(7):e0008332. doi: 10.1371/journal.pntd.0008332. eCollection 2020 Jul. PLoS Negl Trop Dis. 2020. PMID: 32609727 Free PMC article.
H2B.V demarcates divergent strand-switch regions, some tDNA loci, and genome compartments in Trypanosoma cruzi and affects parasite differentiation and host cell invasion.
Rosón JN, Vitarelli MO, Costa-Silva HM, Pereira KS, Pires DDS, Lopes LS, Cordeiro B, Kraus AJ, Cruz KNT, Calderano SG, Fragoso SP, Siegel TN, Elias MC, da Cunha JPC. Rosón JN, et al. Among authors: pires dds. PLoS Pathog. 2022 Feb 18;18(2):e1009694. doi: 10.1371/journal.ppat.1009694. eCollection 2022 Feb. PLoS Pathog. 2022. PMID: 35180281 Free PMC article.