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TLR3 and Rig-like receptor on myeloid dendritic cells and Rig-like receptor on human NK cells are both mandatory for production of IFN-gamma in response to double-stranded RNA.
Perrot I, Deauvieau F, Massacrier C, Hughes N, Garrone P, Durand I, Demaria O, Viaud N, Gauthier L, Blery M, Bonnefoy-Berard N, Morel Y, Tschopp J, Alexopoulou L, Trinchieri G, Paturel C, Caux C. Perrot I, et al. Among authors: demaria o. J Immunol. 2010 Aug 15;185(4):2080-8. doi: 10.4049/jimmunol.1000532. Epub 2010 Jul 16. J Immunol. 2010. PMID: 20639488 Free PMC article.
Harnessing innate immunity in cancer therapy.
Demaria O, Cornen S, Daëron M, Morel Y, Medzhitov R, Vivier E. Demaria O, et al. Nature. 2019 Oct;574(7776):45-56. doi: 10.1038/s41586-019-1593-5. Epub 2019 Oct 2. Nature. 2019. PMID: 31578484 Review.
Immuno-Oncology beyond TILs: Unleashing TILCs.
Demaria O, Vivier E. Demaria O, et al. Cancer Cell. 2020 Apr 13;37(4):428-430. doi: 10.1016/j.ccell.2020.03.021. Cancer Cell. 2020. PMID: 32289267 Free article.
Association of COVID-19 inflammation with activation of the C5a-C5aR1 axis.
Carvelli J, Demaria O, Vély F, Batista L, Chouaki Benmansour N, Fares J, Carpentier S, Thibult ML, Morel A, Remark R, André P, Represa A, Piperoglou C; Explore COVID-19 IPH group; Explore COVID-19 Marseille Immunopole group; Cordier PY, Le Dault E, Guervilly C, Simeone P, Gainnier M, Morel Y, Ebbo M, Schleinitz N, Vivier E. Carvelli J, et al. Among authors: demaria o. Nature. 2020 Dec;588(7836):146-150. doi: 10.1038/s41586-020-2600-6. Epub 2020 Jul 29. Nature. 2020. PMID: 32726800 Free PMC article.
ISACs take a Toll on tumors.
Demaria O, Vivier E. Demaria O, et al. Nat Cancer. 2021 Jan;2(1):12-13. doi: 10.1038/s43018-020-00152-x. Nat Cancer. 2021. PMID: 35121891 No abstract available.
Avdoralimab (Anti-C5aR1 mAb) Versus Placebo in Patients With Severe COVID-19: Results From a Randomized Controlled Trial (FOR COVID Elimination [FORCE]).
Carvelli J, Meziani F, Dellamonica J, Cordier PY, Allardet-Servent J, Fraisse M, Velly L, Barbar SD, Lehingue S, Guervilly C, Desgrouas M, Camou F, Piperoglou C, Vely F, Demaria O, Karakunnel J, Fares J, Batista L, Rotolo F, Viotti J, Boyer-Chammard A, Lacombe K, Le Dault E, Carles M, Schleinitz N, Vivier E; FOR COVID Elimination (FORCE) Study Group. Carvelli J, et al. Among authors: demaria o. Crit Care Med. 2022 Dec 1;50(12):1788-1798. doi: 10.1097/CCM.0000000000005683. Epub 2022 Oct 10. Crit Care Med. 2022. PMID: 36218354 Free PMC article. Clinical Trial.
Antitumor immunity induced by antibody-based natural killer cell engager therapeutics armed with not-alpha IL-2 variant.
Demaria O, Gauthier L, Vetizou M, Blanchard Alvarez A, Vagne C, Habif G, Batista L, Baron W, Belaïd N, Girard-Madoux M, Cesari C, Caratini M, Bosco F, Benac O, Lopez J, Fenis A, Galluso J, Trichard S, Carrette B, Carrette F, Maguer A, Jaubert S, Sansaloni A, Letay-Drouet R, Kosthowa C, Lovera N, Dujardin A, Chanuc F, Le Van M, Bokobza S, Jarmuzynski N, Fos C, Gourdin N, Remark R, Lechevallier E, Fakhry N, Salas S, Deville JL, Le Grand R, Bonnafous C, Vollmy L, Represa A, Carpentier S, Rossi B, Morel A, Cornen S, Perrot I, Morel Y, Vivier E. Demaria O, et al. Cell Rep Med. 2022 Oct 18;3(10):100783. doi: 10.1016/j.xcrm.2022.100783. Cell Rep Med. 2022. PMID: 36260981 Free PMC article.
34 results