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Active learning of enhancers and silencers in the developing neural retina.
Friedman RZ, Ramu A, Lichtarge S, Wu Y, Tripp L, Lyon D, Myers CA, Granas DM, Gause M, Corbo JC, Cohen BA, White MA. Friedman RZ, et al. Among authors: lyon d. Cell Syst. 2025 Jan 15;16(1):101163. doi: 10.1016/j.cels.2024.12.004. Epub 2025 Jan 7. Cell Syst. 2025. PMID: 39778579 Free article.
Safer and efficient base editing and prime editing via ribonucleoproteins delivered through optimized lipid-nanoparticle formulations.
Hołubowicz R, Du SW, Felgner J, Smidak R, Choi EH, Palczewska G, Menezes CR, Dong Z, Gao F, Medani O, Yan AL, Hołubowicz MW, Chen PZ, Bassetto M, Risaliti E, Salom D, Workman JN, Kiser PD, Foik AT, Lyon DC, Newby GA, Liu DR, Felgner PL, Palczewski K. Hołubowicz R, et al. Among authors: lyon dc. Nat Biomed Eng. 2025 Jan;9(1):57-78. doi: 10.1038/s41551-024-01296-2. Epub 2024 Nov 28. Nat Biomed Eng. 2025. PMID: 39609561
Interleukin-15-armoured GPC3 CAR T cells for patients with solid cancers.
Steffin D, Ghatwai N, Montalbano A, Rathi P, Courtney AN, Arnett AB, Fleurence J, Sweidan R, Wang T, Zhang H, Masand P, Maris JM, Martinez D, Pogoriler J, Varadarajan N, Thakkar SG, Lyon D, Lapteva N, Zhuyong M, Patel K, Lopez-Terrada D, Ramos CA, Lulla P, Armaghany T, Grilley BJ, Gottschalk S, Dotti G, Metelitsa LS, Heslop HE, Brenner MK, Sumazin P, Heczey A. Steffin D, et al. Among authors: lyon d. Nature. 2025 Jan;637(8047):940-946. doi: 10.1038/s41586-024-08261-8. Epub 2024 Nov 27. Nature. 2025. PMID: 39604730
633 results