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Translational engagement of lysophosphatidic acid receptor 1 in skin fibrosis: from dermal fibroblasts of patients with scleroderma to tight skin 1 mouse.
Ledein L, Léger B, Dees C, Beyer C, Distler A, Vettori S, Boukaiba R, Bidouard JP, Schaefer M, Pernerstorfer J, Ruetten H, Jagerschmidt A, Janiak P, Distler JHW, Distler O, Illiano S. Ledein L, et al. Among authors: distler jhw, distler a, distler o. Br J Pharmacol. 2020 Sep;177(18):4296-4309. doi: 10.1111/bph.15190. Epub 2020 Aug 5. Br J Pharmacol. 2020. PMID: 32627178 Free PMC article.
Bucillamine induces the synthesis of vascular endothelial growth factor dose-dependently in systemic sclerosis fibroblasts via nuclear factor-kappaB and simian virus 40 promoter factor 1 pathways.
Distler JH, Hagen C, Hirth A, Müller-Ladner U, Lorenz HM, del Rosso A, Michel BA, Gay RE, Nanagara R, Nishioka K, Matucci-Cerinic M, Kalden JR, Gay S, Distler O. Distler JH, et al. Mol Pharmacol. 2004 Feb;65(2):389-99. doi: 10.1124/mol.65.2.389. Mol Pharmacol. 2004. PMID: 14742681
401 results