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Therapeutic potential of novel Cell Division Cycle Kinase 7 inhibitors on TDP-43-related pathogenesis such as Frontotemporal Lobar Degeneration (FTLD) and amyotrophic lateral sclerosis (ALS).
Vaca G, Martinez-Gonzalez L, Fernandez A, Rojas-Prats E, Porras G, Cuevas EP, Gil C, Martinez A, Martin-Requero Á. Vaca G, et al. Among authors: cuevas ep. J Neurochem. 2021 Feb;156(3):379-390. doi: 10.1111/jnc.15118. Epub 2020 Jul 17. J Neurochem. 2021. PMID: 32628315 Free article.
From Kinase Inhibitors to Multitarget Ligands as Powerful Drug Leads for Alzheimer's Disease using Protein-Templated Synthesis.
Nozal V, García-Rubia A, Cuevas EP, Pérez C, Tosat-Bitrián C, Bartolomé F, Carro E, Ramírez D, Palomo V, Martínez A. Nozal V, et al. Among authors: cuevas ep. Angew Chem Int Ed Engl. 2021 Aug 23;60(35):19344-19354. doi: 10.1002/anie.202106295. Epub 2021 Jul 26. Angew Chem Int Ed Engl. 2021. PMID: 34169618 Free PMC article.
New Functions of Intracellular LOXL2: Modulation of RNA-Binding Proteins.
Eraso P, Mazón MJ, Jiménez V, Pizarro-García P, Cuevas EP, Majuelos-Melguizo J, Morillo-Bernal J, Cano A, Portillo F. Eraso P, et al. Among authors: cuevas ep. Molecules. 2023 May 30;28(11):4433. doi: 10.3390/molecules28114433. Molecules. 2023. PMID: 37298909 Free PMC article.
RNAi-mediated silencing of insulin receptor substrate-4 enhances actinomycin D- and tumor necrosis factor-alpha-induced cell death in hepatocarcinoma cancer cell lines.
Cuevas EP, Escribano O, Monserrat J, Martínez-Botas J, Sánchez MG, Chiloeches A, Hernández-Breijo B, Sánchez-Alonso V, Román ID, Fernández-Moreno MD, Guijarro LG. Cuevas EP, et al. J Cell Biochem. 2009 Dec 15;108(6):1292-301. doi: 10.1002/jcb.22359. J Cell Biochem. 2009. PMID: 19795387
Lysyl oxidase-like 2 (LOXL2), a new regulator of cell polarity required for metastatic dissemination of basal-like breast carcinomas.
Moreno-Bueno G, Salvador F, Martín A, Floristán A, Cuevas EP, Santos V, Montes A, Morales S, Castilla MA, Rojo-Sebastián A, Martínez A, Hardisson D, Csiszar K, Portillo F, Peinado H, Palacios J, Cano A. Moreno-Bueno G, et al. Among authors: cuevas ep. EMBO Mol Med. 2011 Sep;3(9):528-44. doi: 10.1002/emmm.201100156. Epub 2011 Jul 6. EMBO Mol Med. 2011. PMID: 21732535 Free PMC article.
Preclinical evaluation of azathioprine plus buthionine sulfoximine in the treatment of human hepatocarcinoma and colon carcinoma.
Hernández-Breijo B, Monserrat J, Ramírez-Rubio S, Cuevas EP, Vara D, Díaz-Laviada I, Fernández-Moreno MD, Román ID, Gisbert JP, Guijarro LG. Hernández-Breijo B, et al. Among authors: cuevas ep. World J Gastroenterol. 2011 Sep 14;17(34):3899-911. doi: 10.3748/wjg.v17.i34.3899. World J Gastroenterol. 2011. PMID: 22025878 Free PMC article.
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