Głuch-Lutwin M - Search Results

1

8-Benzylaminoxanthine scaffold variations for selective ligands acting on adenosine A_2A receptors. Design, synthesis and biological evaluation.

Załuski M, Schabikowski J, Jaśko P, Bryła A, Olejarz-Maciej A, Kaleta M, Głuch-Lutwin M, Brockmann A, Hinz S, Zygmunt M, Kuder K, Latacz G, Vielmuth C, Müller CE, Kieć-Kononowicz K. Załuski M, et al. Bioorg Chem. 2020 Aug;101:104033. doi: 10.1016/j.bioorg.2020.104033. Epub 2020 Jun 19. Bioorg Chem. 2020. PMID: 32629282

2

A Comparison of the Anorectic Effect and Safety of the Alpha2-Adrenoceptor Ligands Guanfacine and Yohimbine in Rats with Diet-Induced Obesity.

Dudek M, Knutelska J, Bednarski M, Nowiński L, Zygmunt M, Mordyl B, Głuch-Lutwin M, Kazek G, Sapa J, Pytka K. Dudek M, et al. PLoS One. 2015 Oct 27;10(10):e0141327. doi: 10.1371/journal.pone.0141327. eCollection 2015. PLoS One. 2015. PMID: 26506439 Free PMC article.

3

Pyrrolidin-2-one derivatives may reduce body weight in rats with diet-induced obesity.

Dudek M, Knutelska J, Bednarski M, Nowiński L, Zygmunt M, Kazek G, Mordyl B, Głuch-Lutwin M, Zaręba P, Kulig K, Sapa J. Dudek M, et al. Eur J Pharmacol. 2016 Apr 5;776:146-55. doi: 10.1016/j.ejphar.2016.02.047. Epub 2016 Feb 17. Eur J Pharmacol. 2016. PMID: 26896778

4

HBK-7 - A new xanthone derivative and a 5-HT1A receptor antagonist with antidepressant-like properties.

Pytka K, Kazek G, Siwek A, Mordyl B, Głuch-Lutwin M, Rapacz A, Olczyk A, Gałuszka A, Waszkielewicz A, Marona H, Sapa J, Filipek B, Zygmunt M. Pytka K, et al. Pharmacol Biochem Behav. 2016 Jul-Aug;146-147:35-43. doi: 10.1016/j.pbb.2016.04.005. Epub 2016 Apr 27. Pharmacol Biochem Behav. 2016. PMID: 27132236

5

Synthesis and activity of newly designed aroxyalkyl or aroxyethoxyethyl derivatives of piperazine on the cardiovascular and the central nervous systems.

Waszkielewicz AM, Kubacka M, Pańczyk K, Mogilski S, Siwek A, Głuch-Lutwin M, Gryboś A, Filipek B. Waszkielewicz AM, et al. Bioorg Med Chem Lett. 2016 Nov 1;26(21):5315-5321. doi: 10.1016/j.bmcl.2016.09.037. Epub 2016 Sep 15. Bioorg Med Chem Lett. 2016. PMID: 27692547

6

Aryl-1,3,5-triazine ligands of histamine H₄ receptor attenuate inflammatory and nociceptive response to carrageen, zymosan and lipopolysaccharide.

Mogilski S, Kubacka M, Łażewska D, Więcek M, Głuch-Lutwin M, Tyszka-Czochara M, Bukowska-Strakova K, Filipek B, Kieć-Kononowicz K. Mogilski S, et al. Inflamm Res. 2017 Jan;66(1):79-95. doi: 10.1007/s00011-016-0997-z. Epub 2016 Oct 20. Inflamm Res. 2017. PMID: 27766379 Free PMC article.

7

Synthesis of a new series of aryl/heteroarylpiperazinyl derivatives of 8-acetyl-7-hydroxy-4-methylcoumarin with low nanomolar 5-HT_1A affinities.

Ostrowska K, Młodzikowska K, Głuch-Lutwin M, Gryboś A, Siwek A. Ostrowska K, et al. Eur J Med Chem. 2017 Sep 8;137:108-116. doi: 10.1016/j.ejmech.2017.05.047. Epub 2017 May 26. Eur J Med Chem. 2017. PMID: 28575721

8

5-HT_1A and 5-HT_2A receptors affinity, docking studies and pharmacological evaluation of a series of 8-acetyl-7-hydroxy-4-methylcoumarin derivatives.

Ostrowska K, Grzeszczuk D, Głuch-Lutwin M, Gryboś A, Siwek A, Leśniak A, Sacharczuk M, Trzaskowski B. Ostrowska K, et al. Bioorg Med Chem. 2018 Jan 15;26(2):527-535. doi: 10.1016/j.bmc.2017.12.016. Epub 2017 Dec 9. Bioorg Med Chem. 2018. PMID: 29269256

9

Novel Multitarget-Directed Ligands Aiming at Symptoms and Causes of Alzheimer's Disease.

Więckowska A, Wichur T, Godyń J, Bucki A, Marcinkowska M, Siwek A, Więckowski K, Zaręba P, Knez D, Głuch-Lutwin M, Kazek G, Latacz G, Mika K, Kołaczkowski M, Korabecny J, Soukup O, Benkova M, Kieć-Kononowicz K, Gobec S, Malawska B. Więckowska A, et al. ACS Chem Neurosci. 2018 May 16;9(5):1195-1214. doi: 10.1021/acschemneuro.8b00024. Epub 2018 Feb 13. ACS Chem Neurosci. 2018. PMID: 29384656

10

Synthesis and activity of di- or trisubstituted N-(phenoxyalkyl)- or N-{2-[2-(phenoxy)ethoxy]ethyl}piperazine derivatives on the central nervous system.

Pańczyk K, Pytka K, Jakubczyk M, Rapacz A, Sałat K, Furgała A, Siwek A, Głuch-Lutwin M, Gryboś A, Słoczyńska K, Pękala E, Żmudzki P, Bucki A, Kołaczkowski M, Żelaszczyk D, Marona H, Waszkielewicz AM. Pańczyk K, et al. Bioorg Med Chem Lett. 2018 Jun 15;28(11):2039-2049. doi: 10.1016/j.bmcl.2018.04.059. Epub 2018 Apr 25. Bioorg Med Chem Lett. 2018. PMID: 29730027

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