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Real-world data confirm the effectiveness of caplacizumab in acquired thrombotic thrombocytopenic purpura.
Völker LA, Kaufeld J, Miesbach W, Brähler S, Reinhardt M, Kühne L, Mühlfeld A, Schreiber A, Gaedeke J, Tölle M, Jabs WJ, Özcan F, Markau S, Girndt M, Bauer F, Westhoff TH, Felten H, Hausberg M, Brand M, Gerth J, Bieringer M, Bommer M, Zschiedrich S, Schneider J, Elitok S, Gawlik A, Gäckler A, Kribben A, Schwenger V, Schoenermarck U, Roeder M, Radermacher J, Bramstedt J, Morgner A, Herbst R, Harth A, Potthoff SA, von Auer C, Wendt R, Christ H, Brinkkoetter PT, Menne J. Völker LA, et al. Among authors: brinkkoetter pt. Blood Adv. 2020 Jul 14;4(13):3085-3092. doi: 10.1182/bloodadvances.2020001973. Blood Adv. 2020. PMID: 32634236 Free PMC article.
ADAMTS13 and VWF activities guide individualized caplacizumab treatment in patients with aTTP.
Völker LA, Kaufeld J, Miesbach W, Brähler S, Reinhardt M, Kühne L, Mühlfeld A, Schreiber A, Gaedeke J, Tölle M, Jabs WJ, Özcan F, Markau S, Girndt M, Bauer F, Westhoff TH, Felten H, Hausberg M, Brand M, Gerth J, Bieringer M, Bommer M, Zschiedrich S, Schneider J, Elitok S, Gawlik A, Gäckler A, Kribben A, Schwenger V, Schoenermarck U, Roeder M, Radermacher J, Bramstedt J, Morgner A, Herbst R, Harth A, Potthoff SA, von Auer C, Wendt R, Christ H, Brinkkoetter PT, Menne J. Völker LA, et al. Among authors: brinkkoetter pt. Blood Adv. 2020 Jul 14;4(13):3093-3101. doi: 10.1182/bloodadvances.2020001987. Blood Adv. 2020. PMID: 32634237 Free PMC article.
Caplacizumab: frequent local skin reactions.
Kaufeld J, Brinkkoetter PT, Schreiber A, Jabs WJ, Bieringer M, Bruck H, Menne J, Völker LA. Kaufeld J, et al. Among authors: brinkkoetter pt. Ann Hematol. 2021 Dec;100(12):3051-3052. doi: 10.1007/s00277-020-04260-7. Epub 2020 Sep 30. Ann Hematol. 2021. PMID: 32997190 Free PMC article. No abstract available.
First use of the anti-VWF nanobody caplacizumab to treat iTTP in pregnancy.
Kühne L, Völker LA, Hagmann H, Hägele H, Osterholt T, Eichenauer DA, Thomas A, Breuer J, Grüttner B, Gottschalk I, Kann M, Benzing T, Thevis M, Müller AM, Brinkkoetter PT. Kühne L, et al. Among authors: brinkkoetter pt. Br J Haematol. 2022 Feb;196(3):e30-e33. doi: 10.1111/bjh.17833. Epub 2021 Sep 29. Br J Haematol. 2022. PMID: 34585743 No abstract available.
Alternate-day dosing of caplacizumab for immune-mediated thrombotic thrombocytopenic purpura.
Kühne L, Kaufeld J, Völker LA, Wendt R, Schönermarck U, Hägele H, Osterholt T, Eichenauer DA, Bieringer M, von Bergwelt-Baildon A, Fischereder M, Buxhofer-Ausch V, Menne J, Brinkkoetter PT, Knöbl P. Kühne L, et al. Among authors: brinkkoetter pt. J Thromb Haemost. 2022 Apr;20(4):951-960. doi: 10.1111/jth.15637. Epub 2022 Jan 23. J Thromb Haemost. 2022. PMID: 35000278 Free article.
78 results