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Oxidative stress and DNA lesions: the role of 8-oxoguanine lesions in Trypanosoma cruzi cell viability.
Aguiar PH, Furtado C, Repolês BM, Ribeiro GA, Mendes IC, Peloso EF, Gadelha FR, Macedo AM, Franco GR, Pena SD, Teixeira SM, Vieira LQ, Guarneri AA, Andrade LO, Machado CR. Aguiar PH, et al. Among authors: machado cr. PLoS Negl Trop Dis. 2013 Jun 13;7(6):e2279. doi: 10.1371/journal.pntd.0002279. Print 2013. PLoS Negl Trop Dis. 2013. PMID: 23785540 Free PMC article.
Unveiling benznidazole's mechanism of action through overexpression of DNA repair proteins in Trypanosoma cruzi.
Rajão MA, Furtado C, Alves CL, Passos-Silva DG, de Moura MB, Schamber-Reis BL, Kunrath-Lima M, Zuma AA, Vieira-da-Rocha JP, Garcia JB, Mendes IC, Pena SD, Macedo AM, Franco GR, de Souza-Pinto NC, de Medeiros MH, Cruz AK, Motta MC, Teixeira SM, Machado CR. Rajão MA, et al. Among authors: machado cr. Environ Mol Mutagen. 2014 May;55(4):309-21. doi: 10.1002/em.21839. Epub 2013 Dec 18. Environ Mol Mutagen. 2014. PMID: 24347026
Distinct Phenotypes Caused by Mutation of MSH2 in Trypanosome Insect and Mammalian Life Cycle Forms Are Associated with Parasite Adaptation to Oxidative Stress.
Grazielle-Silva V, Zeb TF, Bolderson J, Campos PC, Miranda JB, Alves CL, Machado CR, McCulloch R, Teixeira SM. Grazielle-Silva V, et al. Among authors: machado cr. PLoS Negl Trop Dis. 2015 Jun 17;9(6):e0003870. doi: 10.1371/journal.pntd.0003870. eCollection 2015 Jun. PLoS Negl Trop Dis. 2015. PMID: 26083967 Free PMC article.
Catalase expression impairs oxidative stress-mediated signalling in Trypanosoma cruzi.
Freire ACG, Alves CL, Goes GR, Resende BC, Moretti NS, Nunes VS, Aguiar PHN, Tahara EB, Franco GR, Macedo AM, Pena SDJ, Gadelha FR, Guarneri AA, Schenkman S, Vieira LQ, Machado CR. Freire ACG, et al. Among authors: machado cr. Parasitology. 2017 Sep;144(11):1498-1510. doi: 10.1017/S0031182017001044. Epub 2017 Jun 27. Parasitology. 2017. PMID: 28653592
Characterization of Trypanosoma cruzi MutY DNA glycosylase ortholog and its role in oxidative stress response.
Kunrath-Lima M, Repolês BM, Alves CL, Furtado C, Rajão MA, Macedo AM, Franco GR, Pena SDJ, Valenzuela L, Wisnovsky S, Kelley SO, Galanti N, Cabrera G, Machado CR. Kunrath-Lima M, et al. Among authors: machado cr. Infect Genet Evol. 2017 Nov;55:332-342. doi: 10.1016/j.meegid.2017.09.030. Epub 2017 Sep 29. Infect Genet Evol. 2017. PMID: 28970112
The recombinase Rad51 plays a key role in events of genetic exchange in Trypanosoma cruzi.
Alves CL, Repolês BM, da Silva MS, Mendes IC, Marin PA, Aguiar PHN, Santos SDS, Franco GR, Macedo AM, Pena SDJ, Andrade LO, Guarneri AA, Tahara EB, Elias MC, Machado CR. Alves CL, et al. Among authors: machado cr. Sci Rep. 2018 Sep 6;8(1):13335. doi: 10.1038/s41598-018-31541-z. Sci Rep. 2018. PMID: 30190603 Free PMC article.
212 results