Pommier Y - Search Results

1

Resistance to the CHK1 inhibitor prexasertib involves functionally distinct CHK1 activities in BRCA wild-type ovarian cancer.

Nair J, Huang TT, Murai J, Haynes B, Steeg PS, Pommier Y, Lee JM. Nair J, et al. Among authors: pommier y. Oncogene. 2020 Aug;39(33):5520-5535. doi: 10.1038/s41388-020-1383-4. Epub 2020 Jul 9. Oncogene. 2020. PMID: 32647134 Free PMC article.

2

Apoptosis defects and chemotherapy resistance: molecular interaction maps and networks.

Pommier Y, Sordet O, Antony S, Hayward RL, Kohn KW. Pommier Y, et al. Oncogene. 2004 Apr 12;23(16):2934-49. doi: 10.1038/sj.onc.1207515. Oncogene. 2004. PMID: 15077155 Review.

3

p21CDKN1A allows the repair of replication-mediated DNA double-strand breaks induced by topoisomerase I and is inactivated by the checkpoint kinase inhibitor 7-hydroxystaurosporine.

Furuta T, Hayward RL, Meng LH, Takemura H, Aune GJ, Bonner WM, Aladjem MI, Kohn KW, Pommier Y. Furuta T, et al. Among authors: pommier y. Oncogene. 2006 May 11;25(20):2839-49. doi: 10.1038/sj.onc.1209313. Oncogene. 2006. PMID: 16407843

4

Dose-response transition from cell cycle arrest to apoptosis with selective degradation of Mdm2 and p21WAF1/CIP1 in response to the novel anticancer agent, aminoflavone (NSC 686,288).

Meng LH, Kohn KW, Pommier Y. Meng LH, et al. Among authors: pommier y. Oncogene. 2007 Jul 19;26(33):4806-16. doi: 10.1038/sj.onc.1210283. Epub 2007 Feb 12. Oncogene. 2007. PMID: 17297446

5

CHEK2 genomic and proteomic analyses reveal genetic inactivation or endogenous activation across the 60 cell lines of the US National Cancer Institute.

Zoppoli G, Solier S, Reinhold WC, Liu H, Connelly JW Jr, Monks A, Shoemaker RH, Abaan OD, Davis SR, Meltzer PS, Doroshow JH, Pommier Y. Zoppoli G, et al. Among authors: pommier y. Oncogene. 2012 Jan 26;31(4):403-18. doi: 10.1038/onc.2011.283. Epub 2011 Jul 18. Oncogene. 2012. PMID: 21765476 Free PMC article.

6

Potentiation of the novel topoisomerase I inhibitor indenoisoquinoline LMP-400 by the cell checkpoint and Chk1-Chk2 inhibitor AZD7762.

Aris SM, Pommier Y. Aris SM, et al. Among authors: pommier y. Cancer Res. 2012 Feb 15;72(4):979-89. doi: 10.1158/0008-5472.CAN-11-2579. Epub 2011 Dec 21. Cancer Res. 2012. PMID: 22189968 Free PMC article.

7

Trapping of PARP1 and PARP2 by Clinical PARP Inhibitors.

Murai J, Huang SY, Das BB, Renaud A, Zhang Y, Doroshow JH, Ji J, Takeda S, Pommier Y. Murai J, et al. Among authors: pommier y. Cancer Res. 2012 Nov 1;72(21):5588-99. doi: 10.1158/0008-5472.CAN-12-2753. Cancer Res. 2012. PMID: 23118055 Free PMC article.

8

TDP1 repairs nuclear and mitochondrial DNA damage induced by chain-terminating anticancer and antiviral nucleoside analogs.

Huang SY, Murai J, Dalla Rosa I, Dexheimer TS, Naumova A, Gmeiner WH, Pommier Y. Huang SY, et al. Among authors: pommier y. Nucleic Acids Res. 2013 Sep;41(16):7793-803. doi: 10.1093/nar/gkt483. Epub 2013 Jun 17. Nucleic Acids Res. 2013. PMID: 23775789 Free PMC article.

9

Differential and common DNA repair pathways for topoisomerase I- and II-targeted drugs in a genetic DT40 repair cell screen panel.

Maede Y, Shimizu H, Fukushima T, Kogame T, Nakamura T, Miki T, Takeda S, Pommier Y, Murai J. Maede Y, et al. Among authors: pommier y. Mol Cancer Ther. 2014 Jan;13(1):214-20. doi: 10.1158/1535-7163.MCT-13-0551. Epub 2013 Oct 15. Mol Cancer Ther. 2014. PMID: 24130054 Free PMC article.

10

Stereospecific PARP trapping by BMN 673 and comparison with olaparib and rucaparib.

Murai J, Huang SY, Renaud A, Zhang Y, Ji J, Takeda S, Morris J, Teicher B, Doroshow JH, Pommier Y. Murai J, et al. Among authors: pommier y. Mol Cancer Ther. 2014 Feb;13(2):433-43. doi: 10.1158/1535-7163.MCT-13-0803. Epub 2013 Dec 19. Mol Cancer Ther. 2014. PMID: 24356813 Free PMC article.

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