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Page 1
STK11 (LKB1) missense somatic mutant isoforms promote tumor growth, motility and inflammation.
Granado-Martínez P, Garcia-Ortega S, González-Sánchez E, McGrail K, Selgas R, Grueso J, Gil R, Naldaiz-Gastesi N, Rhodes AC, Hernandez-Losa J, Ferrer B, Canals F, Villanueva J, Méndez O, Espinosa-Gil S, Lizcano JM, Muñoz-Couselo E, García-Patos V, Recio JA. Granado-Martínez P, et al. Commun Biol. 2020 Jul 9;3(1):366. doi: 10.1038/s42003-020-1092-0. Commun Biol. 2020. PMID: 32647375 Free PMC article.
Loss of Lkb1 cooperates with BrafV600E and ultraviolet radiation, increasing melanoma multiplicity and neural-like dedifferentiation.
McGrail K, González-Sánchez E, Granado-Martínez P, Orsenigo R, Ding Y, Ferrer B, Hernández-Losa J, Ortega I, Martín-Caballero J, Muñoz-Couselo E, García-Patos V, Recio JA. McGrail K, et al. Among authors: granado martinez p. Mol Oncol. 2024 Aug 8. doi: 10.1002/1878-0261.13715. Online ahead of print. Mol Oncol. 2024. PMID: 39115053 Free article.
BRAF activation by metabolic stress promotes glycolysis sensitizing NRASQ61-mutated melanomas to targeted therapy.
McGrail K, Granado-Martínez P, Esteve-Puig R, García-Ortega S, Ding Y, Sánchez-Redondo S, Ferrer B, Hernandez-Losa J, Canals F, Manzano A, Navarro-Sabaté A, Bartrons R, Yanes O, Pérez-Alea M, Muñoz-Couselo E, Garcia-Patos V, Recio JA. McGrail K, et al. Among authors: granado martinez p. Nat Commun. 2022 Nov 19;13(1):7113. doi: 10.1038/s41467-022-34907-0. Nat Commun. 2022. PMID: 36402789 Free PMC article.