Hofmann U - Search Results

1

Progesterone receptor membrane component 1 regulates lipid homeostasis and drives oncogenic signaling resulting in breast cancer progression.

Asperger H, Stamm N, Gierke B, Pawlak M, Hofmann U, Zanger UM, Marton A, Katona RL, Buhala A, Vizler C, Cieslik JP, Ruckhäberle E, Niederacher D, Fehm T, Neubauer H, Ludescher M. Asperger H, et al. Among authors: hofmann u. Breast Cancer Res. 2020 Jul 13;22(1):75. doi: 10.1186/s13058-020-01312-8. Breast Cancer Res. 2020. PMID: 32660617 Free PMC article.

2

Extensive genetic polymorphism in the human CYP2B6 gene with impact on expression and function in human liver.

Lang T, Klein K, Fischer J, Nüssler AK, Neuhaus P, Hofmann U, Eichelbaum M, Schwab M, Zanger UM. Lang T, et al. Among authors: hofmann u. Pharmacogenetics. 2001 Jul;11(5):399-415. doi: 10.1097/00008571-200107000-00004. Pharmacogenetics. 2001. PMID: 11470993

3

Sensitive method for the quantification of urinary pyrimidine metabolites in healthy adults by gas chromatography-tandem mass spectrometry.

Hofmann U, Schwab M, Seefried S, Marx C, Zanger UM, Eichelbaum M, Mürdter TE. Hofmann U, et al. J Chromatogr B Analyt Technol Biomed Life Sci. 2003 Jul 5;791(1-2):371-80. doi: 10.1016/s1570-0232(03)00251-4. J Chromatogr B Analyt Technol Biomed Life Sci. 2003. PMID: 12798197

4

Role of genetic and nongenetic factors for fluorouracil treatment-related severe toxicity: a prospective clinical trial by the German 5-FU Toxicity Study Group.

Schwab M, Zanger UM, Marx C, Schaeffeler E, Klein K, Dippon J, Kerb R, Blievernicht J, Fischer J, Hofmann U, Bokemeyer C, Eichelbaum M; German 5-FU Toxicity Study Group. Schwab M, et al. Among authors: hofmann u. J Clin Oncol. 2008 May 1;26(13):2131-8. doi: 10.1200/JCO.2006.10.4182. Epub 2008 Feb 25. J Clin Oncol. 2008. PMID: 18299612 Clinical Trial.

5

A predominate role of CYP1A2 for the metabolism of nabumetone to the active metabolite, 6-methoxy-2-naphthylacetic acid, in human liver microsomes.

Turpeinen M, Hofmann U, Klein K, Mürdter T, Schwab M, Zanger UM. Turpeinen M, et al. Among authors: hofmann u. Drug Metab Dispos. 2009 May;37(5):1017-24. doi: 10.1124/dmd.108.025700. Epub 2009 Feb 9. Drug Metab Dispos. 2009. PMID: 19204080

6

UDP-glucuronosyltransferase (UGT) polymorphisms affect atorvastatin lactonization in vitro and in vivo.

Riedmaier S, Klein K, Hofmann U, Keskitalo JE, Neuvonen PJ, Schwab M, Niemi M, Zanger UM. Riedmaier S, et al. Among authors: hofmann u. Clin Pharmacol Ther. 2010 Jan;87(1):65-73. doi: 10.1038/clpt.2009.181. Epub 2009 Sep 30. Clin Pharmacol Ther. 2010. PMID: 19794410

7

Profiling induction of cytochrome p450 enzyme activity by statins using a new liquid chromatography-tandem mass spectrometry cocktail assay in human hepatocytes.

Feidt DM, Klein K, Hofmann U, Riedmaier S, Knobeloch D, Thasler WE, Weiss TS, Schwab M, Zanger UM. Feidt DM, et al. Among authors: hofmann u. Drug Metab Dispos. 2010 Sep;38(9):1589-97. doi: 10.1124/dmd.110.033886. Epub 2010 Jun 15. Drug Metab Dispos. 2010. PMID: 20551241

8

Paraoxonase (PON1 and PON3) Polymorphisms: Impact on Liver Expression and Atorvastatin-Lactone Hydrolysis.

Riedmaier S, Klein K, Winter S, Hofmann U, Schwab M, Zanger UM. Riedmaier S, et al. Among authors: hofmann u. Front Pharmacol. 2011 Jul 27;2:41. doi: 10.3389/fphar.2011.00041. eCollection 2011. Front Pharmacol. 2011. PMID: 21852972 Free PMC article.

9

DNA methylation is associated with downregulation of the organic cation transporter OCT1 (SLC22A1) in human hepatocellular carcinoma.

Schaeffeler E, Hellerbrand C, Nies AT, Winter S, Kruck S, Hofmann U, van der Kuip H, Zanger UM, Koepsell H, Schwab M. Schaeffeler E, et al. Among authors: hofmann u. Genome Med. 2011 Dec 23;3(12):82. doi: 10.1186/gm298. Genome Med. 2011. PMID: 22196450 Free PMC article.

10

A systematic comparison of the impact of inflammatory signaling on absorption, distribution, metabolism, and excretion gene expression and activity in primary human hepatocytes and HepaRG cells.

Klein M, Thomas M, Hofmann U, Seehofer D, Damm G, Zanger UM. Klein M, et al. Among authors: hofmann u. Drug Metab Dispos. 2015 Feb;43(2):273-83. doi: 10.1124/dmd.114.060962. Epub 2014 Dec 5. Drug Metab Dispos. 2015. PMID: 25480923

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