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A coagulation defect arising from heterozygous premature termination of tissue factor.
Schulman S, El-Darzi E, Florido MH, Friesen M, Merrill-Skoloff G, Brake MA, Schuster CR, Lin L, Westrick RJ, Cowan CA, Flaumenhaft R; NIHR BioResource; Ouwehand WH, Peerlinck K, Freson K, Turro E, Furie B. Schulman S, et al. Among authors: lin l. J Clin Invest. 2020 Oct 1;130(10):5302-5312. doi: 10.1172/JCI133780. J Clin Invest. 2020. PMID: 32663190 Free PMC article.
A substrate-driven allosteric switch that enhances PDI catalytic activity.
Bekendam RH, Bendapudi PK, Lin L, Nag PP, Pu J, Kennedy DR, Feldenzer A, Chiu J, Cook KM, Furie B, Huang M, Hogg PJ, Flaumenhaft R. Bekendam RH, et al. Among authors: lin l. Nat Commun. 2016 Aug 30;7:12579. doi: 10.1038/ncomms12579. Nat Commun. 2016. PMID: 27573496 Free PMC article.
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