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Page 1
In Vitro and Cellular Probes to Study PARP Enzyme Target Engagement.
Wigle TJ, Blackwell DJ, Schenkel LB, Ren Y, Church WD, Desai HJ, Swinger KK, Santospago AG, Majer CR, Lu AZ, Niepel M, Perl NR, Vasbinder MM, Keilhack H, Kuntz KW. Wigle TJ, et al. Among authors: lu az. Cell Chem Biol. 2020 Jul 16;27(7):877-887.e14. doi: 10.1016/j.chembiol.2020.06.009. Cell Chem Biol. 2020. PMID: 32679093 Free article.
A potent and selective PARP14 inhibitor decreases protumor macrophage gene expression and elicits inflammatory responses in tumor explants.
Schenkel LB, Molina JR, Swinger KK, Abo R, Blackwell DJ, Lu AZ, Cheung AE, Church WD, Kunii K, Kuplast-Barr KG, Majer CR, Minissale E, Mo JR, Niepel M, Reik C, Ren Y, Vasbinder MM, Wigle TJ, Richon VM, Keilhack H, Kuntz KW. Schenkel LB, et al. Among authors: lu az. Cell Chem Biol. 2021 Aug 19;28(8):1158-1168.e13. doi: 10.1016/j.chembiol.2021.02.010. Epub 2021 Mar 10. Cell Chem Biol. 2021. PMID: 33705687 Free article.
Targeted Degradation of PARP14 Using a Heterobifunctional Small Molecule.
Wigle TJ, Ren Y, Molina JR, Blackwell DJ, Schenkel LB, Swinger KK, Kuplast-Barr K, Majer CR, Church WD, Lu AZ, Mo J, Abo R, Cheung A, Dorsey BW, Niepel M, Perl NR, Vasbinder MM, Keilhack H, Kuntz KW. Wigle TJ, et al. Among authors: lu az. Chembiochem. 2021 Jun 15;22(12):2107-2110. doi: 10.1002/cbic.202100047. Epub 2021 May 4. Chembiochem. 2021. PMID: 33838082
PARP7 negatively regulates the type I interferon response in cancer cells and its inhibition triggers antitumor immunity.
Gozgit JM, Vasbinder MM, Abo RP, Kunii K, Kuplast-Barr KG, Gui B, Lu AZ, Molina JR, Minissale E, Swinger KK, Wigle TJ, Blackwell DJ, Majer CR, Ren Y, Niepel M, Varsamis ZA, Nayak SP, Bamberg E, Mo JR, Church WD, Mady ASA, Song J, Utley L, Rao PE, Mitchison TJ, Kuntz KW, Richon VM, Keilhack H. Gozgit JM, et al. Among authors: lu az. Cancer Cell. 2021 Sep 13;39(9):1214-1226.e10. doi: 10.1016/j.ccell.2021.06.018. Epub 2021 Jul 22. Cancer Cell. 2021. PMID: 34375612 Free article.
Influence of coronal lumbar Cobb angle and surgical level on short-segment lumbar surgery outcomes in degenerative scoliosis.
Asada T, Simon CZ, Durbas A, Allen MRJ, DiSilvestro KJ, Hirase T, Bovonratwet P, Singh N, Tuma O, Araghi K, Subramanian T, Korsun MK, Zhang J, Kim ET, Kwas CT, Bay A, Lu AZ, Mai E, Kim YE, Vaishnav AS, Dowdell JE, Sheha ED, Qureshi SA, Iyer S. Asada T, et al. Among authors: lu az. Eur Spine J. 2024 Dec 14. doi: 10.1007/s00586-024-08599-7. Online ahead of print. Eur Spine J. 2024. PMID: 39673606
Does Approach Matter? Comparison of Early Postoperative Life-threatening Complications in Elderly Patients With Multilevel Cervical Stenosis.
Asada T, Akosman I, Lovecchio FC, Subramanian T, Shahi P, Maayan O, Singh N, Araghi K, Korsun MK, Tuma OC, Pajak A, Lu AZ, Mai E, Kim YE, Dowdell JE, Sheha ED, Iyer S, Qureshi SA. Asada T, et al. Among authors: lu az. Clin Spine Surg. 2024 Dec 11. doi: 10.1097/BSD.0000000000001692. Online ahead of print. Clin Spine Surg. 2024. PMID: 39660732
Short-segment fusion versus isolated decompression in lumbar spinal canal stenosis patients with Cobb angles over 20 degrees.
Asada T, Simon CZ, Durbas A, Allen MRJ, DiSilvestro KJ, Hirase T, Singh N, Bovonratwet P, Bay A, Subramanian T, Mai E, Kim YE, Korsun MK, Tuma OC, Araghi K, Zhang J, Kim ET, Kwas CT, Lu AZ, Vaishnav AS, Dowdell JE, Sheha ED, Qureshi SA, Iyer S. Asada T, et al. Among authors: lu az. Spine J. 2024 Nov 4:S1529-9430(24)01108-2. doi: 10.1016/j.spinee.2024.10.007. Online ahead of print. Spine J. 2024. PMID: 39505012
Understanding How ChatGPT May Become a Clinical Administrative Tool Through an Investigation on the Ability to Answer Common Patient Questions Concerning Ulnar Collateral Ligament Injuries.
Varady NH, Lu AZ, Mazzucco M, Dines JS, Altchek DW, Williams RJ 3rd, Kunze KN. Varady NH, et al. Among authors: lu az. Orthop J Sports Med. 2024 Jul 31;12(7):23259671241257516. doi: 10.1177/23259671241257516. eCollection 2024 Jul. Orthop J Sports Med. 2024. PMID: 39139744 Free PMC article.
34 results